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OPAC HELP

Titolo:
Therapy with nCPAP: incomplete elimination of Sleep Related Breathing Disorder
Autore:
Grote, L; Hedner, J; Grunstein, R; Kraiczi, H;
Indirizzi:
Sahlgrens Univ Hosp, Dept Clin Pharmacol, S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp Gothenburg Sweden S-41345 S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp, Sleep Lab, S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp Gothenburg Sweden S-41345 S-41345 Gothenburg, Sweden Royal Prince Alfred Hosp, Sleep Disorders Ctr, Sydney, NSW 2050, AustraliaRoyal Prince Alfred Hosp Sydney NSW Australia 2050 y, NSW 2050, Australia
Titolo Testata:
EUROPEAN RESPIRATORY JOURNAL
fascicolo: 5, volume: 16, anno: 2000,
pagine: 921 - 927
SICI:
0903-1936(200011)16:5<921:TWNIEO>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITIVE AIRWAY PRESSURE; NASAL CPAP THERAPY; APNOEA/HYPOPNOEA SYNDROME; APNEA/HYPOPNEA SYNDROME; PATIENT COMPLIANCE; RISK FACTOR; APNEA; FRAGMENTATION; HYPERTENSION; VALIDITY;
Keywords:
compliance; continuous positive airway pressure; effectiveness; efficacy; sleep apnoea; sleep apnoea alleviation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Grote, L Sahlgrens Univ Hosp, Dept Clin Pharmacol, S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp Gothenburg Sweden S-41345 othenburg, Sweden
Citazione:
L. Grote et al., "Therapy with nCPAP: incomplete elimination of Sleep Related Breathing Disorder", EUR RESP J, 16(5), 2000, pp. 921-927

Abstract

Correct assessment of the overall treatment effectiveness requires knowledge about therapy compliance and efficacy. This study aimed to determine overall long-term apnoea alleviation after continuous positive airway pressure(CPAP) in a complete sleep laboratory cohort. Out of 209 consecutive CPAP candidates (mean age 57+/-12 yrs, body mass index (BMI) 30.0+/-5.1 kg.m(2), respiratory disturbance index (RDI) 32.9+/-29h), follow-up treatment was performed in 149 of them at 9, 18 and 30 months after CPAP prescription. Compliance with CPAP (machine run time/days CPAPavailable) was adjusted for the individual subjective sleep-time. Apnoea alleviation was defined as adjusted compliance multiplied by the CPAP effect(RDI with CPAP applied), remaining RDI was calculated. The baseline RDI, age or BMI in 75 patients, who did not tolerate nasal continuous positive airway pressure (nCPAP), did not differ from those accepting CPAP (acceptors, n=74). In accepters at 9 months follow-up RDI with CPAP applied was 1.4+/-2.6 (CPAP effect, n=66), mean CPAP use was 3.6+/-2.5.24h(-1) (n=68), mean apnoea alleviation was 52.4+/-32.0% (range 1-100%, n=47), the average remaining whole-night RDI was 17.8+/-26. At 9, 18 and 30 months (n=47), the mean daily CPAP use increased from 3.6+/-2.5 h to 4.1+/-2.5h and 4.4+/-2.4 h (p<0.01). Effectiveness of continuous positive airway pressure is potentially high but acceptance was low When accounting for sleep-time, its actual effect anduse, only 50% adjusted continuous positive airway pressure effectiveness was observed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/11/20 alle ore 03:34:31