Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Developmental sources of variation in liability to adolescent substance use disorders
Autore:
Dawes, MA; Antelman, SM; Vanyukov, MM; Giancola, P; Tarter, RE; Susman, EJ; Mezzich, A; Clark, DB;
Indirizzi:
Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Dept Psychiat, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 sychiat, Pittsburgh, PA 15213 USA Univ Pittsburgh, Ctr Educ & Drug Abuse Res, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 use Res, Pittsburgh, PA 15261 USA Univ Kentucky, Dept Psychol, Lexington, KY 40506 USA Univ Kentucky Lexington KY USA 40506 ept Psychol, Lexington, KY 40506 USA Penn State Univ, Dept Biobehav Hlth, University Pk, PA 16802 USA Penn State Univ University Pk PA USA 16802 h, University Pk, PA 16802 USA
Titolo Testata:
DRUG AND ALCOHOL DEPENDENCE
fascicolo: 1, volume: 61, anno: 2000,
pagine: 3 - 14
SICI:
0376-8716(200012)61:1<3:DSOVIL>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
PITUITARY-ADRENAL AXIS; POSTTRAUMATIC-STRESS-DISORDER; TIME-DEPENDENT SENSITIZATION; SALIVARY CORTISOL RESPONSES; CORTICAL COGNITIVE FUNCTION; DRUG-USE; AGGRESSIVE-BEHAVIOR; ALCOHOL-ABUSE; LONGITUDINAL EXAMINATION; BIOLOGICAL MATURATION;
Keywords:
liability; puberty; adolescence; affective, cognitive, and behavioral dysregulation; neuroadaptation; substance use disorder;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
170
Recensione:
Indirizzi per estratti:
Indirizzo: Dawes, MA Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Dept Psychiat, 3811 OHara St, Pittsburgh, PA 15213 USA Univ Pittsburgh 3811 OHara St Pittsburgh PA USA 15213 15213 USA
Citazione:
M.A. Dawes et al., "Developmental sources of variation in liability to adolescent substance use disorders", DRUG AL DEP, 61(1), 2000, pp. 3-14

Abstract

This review provides a synthesis of the literature on the complex sequenceof maturational, psychosocial, and neuroadaptive processes that lead to substance use disorders (SUD) in adolescence. A brief overview introduces theconcepts of liability to SUD and epigenesis. A theory is presented explaining how affective, cognitive, and behavioral dysregulation in late childhood is exacerbated during early and middle adolescence by family and peer factors, as well as puberty, leading to substance use. Continued exacerbation of the three components of dysregulation by drug and non-drug stressors during late adolescence is posited to result in neuroadaptations that increasethe likelihood of developing SUD, particularly in high-risk individuals. Implications for etiologic research as well as clinical and preventive interventions are discussed. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 21:09:46