Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
UV transmission measurements of small skin specimens with special quartz cuvettes
Autore:
Hoffmann, K; Kaspar, K; Altmeyer, P; Gambichler, T;
Indirizzi:
Ruhr Univ Bochum, Dept Dermatol, D-44791 Bochum, Germany Ruhr Univ BochumBochum Germany D-44791 ermatol, D-44791 Bochum, Germany
Titolo Testata:
DERMATOLOGY
fascicolo: 4, volume: 201, anno: 2000,
pagine: 307 - 311
SICI:
1018-8665(2000)201:4<307:UTMOSS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN EPIDERMAL LAYERS; RADIATION;
Keywords:
UV transmission; spectrophotometry; quartz glass cuvettes; sunscreens;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Hoffmann, K Ruhr Univ Bochum, Dept Dermatol, Gudrunstr 56, D-44791 Bochum,Germany Ruhr Univ Bochum Gudrunstr 56 Bochum Germany D-44791 Germany
Citazione:
K. Hoffmann et al., "UV transmission measurements of small skin specimens with special quartz cuvettes", DERMATOLOGY, 201(4), 2000, pp. 307-311

Abstract

Background: The penetration of different wavelengths of UV radiation through human skin is of major importance, especially for the determination of photoprotective properties of sunscreens and UV-protective clothes. Objective: In this study we present a new method for the measurement of UV transmission through small skin specimens. Methods: The transmission measurements were performed by using a UV spectrophotometer with an integrating sphere operating in the wavelength range of 280-390 nm. For the skin samples, special quartz glass cuvettes were developed which allowed measurements for very thin and small skin specimens. Furthermore, the cuvettes prevented dehydration of the specimens and guaranteed, by using an additional diaphragm, thatthe transmission data were derived solely from the small skin specimen examined. Specimens measuring 8 x 3 mm(2) with a thickness of 0.3 mm (histometric and sonographic control) were taken from the thighs of 10 subjects via shave biopsy. Results: in the UVA range (315-390 nm) we obtained a mean transmission of 4.6% and for the UVB range (280-315 nm) of 0.9%, No significant (p > 0.14) difference of UV transmission was found between the individualskin specimens. Conclusion: This new method seems to be well suitable for UV transmission measurements of small skin specimens. As UVA radiation has a much deeper penetration depth and in in vivo situations dermal hemoglobincould have an effect on UV penetration, the present method is better suitable for the investigation of UVB-induced biological adaptation mechanisms and the impact of topical agents on UVB transmission of the epidermis. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/07/18 alle ore 13:30:46