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Titolo:
Cytokines and hormones with anti inflammatory effects: new tools for therapeutic intervention
Autore:
Baud, L; Fouqueray, B; Bellocq, A;
Indirizzi:
Hop Tenon, Serv Explorat Fonct Multidisciplinaires, F-75020 Paris, France Hop Tenon Paris France F-75020 ultidisciplinaires, F-75020 Paris, France Hop Tenon, INSERM, U489, F-75020 Paris, France Hop Tenon Paris France F-75020 enon, INSERM, U489, F-75020 Paris, France
Titolo Testata:
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
fascicolo: 1, volume: 10, anno: 2001,
pagine: 49 - 54
SICI:
1062-4821(200101)10:1<49:CAHWAI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR-BINDING AFFINITY; CRESCENTIC GLOMERULONEPHRITIS; GLUCOCORTICOID RECEPTOR; GENE-EXPRESSION; GLOMERULAR INJURY; MESSENGER-RNA; SELF-DEFENSE; DNA-BINDING; TGF-BETA; INTERLEUKIN-4;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Baud, L Hop Tenon, Serv Explorat Fonct Multidisciplinaires, 4 Rue Chine, F-75020 Paris, France Hop Tenon 4 Rue Chine Paris France F-75020 F-75020 Paris, France
Citazione:
L. Baud et al., "Cytokines and hormones with anti inflammatory effects: new tools for therapeutic intervention", CURR OP NEP, 10(1), 2001, pp. 49-54

Abstract

The inflammation that is involved in the development of glomerulonephritisis tightly regulated by the expression of antiinflammatory factors. These include circulating hormones, such as glucocorticoids, and mediators that are produced by intrinsic cells and infiltrating leucocytes. The present review focuses on these anti-inflammatory factors, summarizing in particular their activities in existing models of glomerulonephritis. In addition, experimental evidence is presented that anti-inflammatory mediators are able toincrease glucocorticoid binding or signalling in target cells. These data help to explain the in-vivo efficacy of anti-inflammatory mediators, and offer a promising new avenue for therapeutic intervention. Curr Opin Nephrol Hypertens 10:49-54. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 21:11:52