Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis
Autore:
Young, S; Larkin, G; Branley, M; Lightman, S;
Indirizzi:
Moorfields Eye Hosp, Inst Ophthalmol, Dept Clin Ophthalmol, London EC1V 2PD, England Moorfields Eye Hosp London England EC1V 2PD ol, London EC1V 2PD, England
Titolo Testata:
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
fascicolo: 1, volume: 29, anno: 2001,
pagine: 2 - 6
SICI:
1442-6404(200102)29:1<2:SAEOIT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
BACTERIAL ENDOPHTHALMITIS; EDEMA; ACETAZOLAMIDE; DEGENERATION; INJECTIONS;
Keywords:
macular oedema; steroids; triamcinolone; uveitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Lightman, S Moorfields Eye Hosp, Inst Ophthalmol, Dept Clin Ophthalmol, City Rd, London EC1V 2PD, England Moorfields Eye Hosp City Rd London EnglandEC1V 2PD , England
Citazione:
S. Young et al., "Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis", CLIN EXP OP, 29(1), 2001, pp. 2-6

Abstract

Purpose: To report the safety and efficacy of intravitreal triamcinolone in the treatment of inflammatory cystoid macular oedema (CMO) in six patients who were resistant to other forms of therapy. Methods: An open-label unmasked prospective non- randomized pilot study ofsix patients with idiopathic uveitis and visually significant macular oedema, resistant to periocular and/or systemic corticosteroid treatment, was carried out. Baseline examination and investigations were performed, including fundus fluorescein angiography, and the patients were given a single intravitreal injection of triamcinolone (4 mg/0.1 mL). The primary outcome measure was angiographic resolution of CMO. Patients were reviewed at intervals of 2-4 weeks for 12 months. Results: A single intravitreal injection of triamcinolone induced clinicaland angiographic resolution of inflammatory macular oedema in all patientsfor varying periods of time up to 6 months. Five patients experienced increased intraocular pressure to 30 mmHg or greater which required treatment. Two patients developed posterior subcapsular cataract. Conclusion: One injection of intravitreal triamcinolone was an effective short-term treatment for resistant CMO in uveitis. As with steroids given byother routes, raised intraocular pressure and cataract may occur. As it was so effective in these eyes with resistant CMO, a larger study is warranted to evaluate this form of therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:12:31