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Titolo:
Result of neoadjuvant therapy in mammary carcinomas
Autore:
Winzer, KJ;
Indirizzi:
Humboldt Univ, Klin Allgemein Viszeral Gefass & Thoraxchirurg, D-10117 Berlin, Germany Humboldt Univ Berlin Germany D-10117 raxchirurg, D-10117 Berlin, Germany
Titolo Testata:
CHIRURG
fascicolo: 12, volume: 71, anno: 2000,
pagine: 1458 - 1465
SICI:
0009-4722(200012)71:12<1458:RONTIM>2.0.ZU;2-I
Fonte:
ISI
Lingua:
GER
Soggetto:
OPERABLE BREAST-CANCER; LYMPH-NODE METASTASES; RANDOMIZED TRIAL; PREMENOPAUSAL WOMEN; CHEMOTHERAPY; CYCLOPHOSPHAMIDE; FLUOROURACIL; CONSERVATION; DOXORUBICIN; SURGERY;
Keywords:
breast cancer; neoadjuvant therapy; breast-conserving surgery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Winzer, KJ Humboldt Univ, Klin Allgemein Viszeral Gefass & Thoraxchirurg, Univ Klinikum Charite Campus Mitte,Schumannstr 20, D-10117 Berlin, Germany Humboldt Univ Univ Klinikum Charite Campus Mitte,Schumannstr 20 Berlin Germany D-10117
Citazione:
K.J. Winzer, "Result of neoadjuvant therapy in mammary carcinomas", CHIRURG, 71(12), 2000, pp. 1458-1465

Abstract

For 20 years preoperative chemotherapy has been the treatment of choice ininflammatory breast cancer. Adjuvant chemotherapy does not show any advantages over neoadjuvant systemic chemotherapy in terms of survival of patients with breast cancer. Reduction of the size of the tumor enables the surgeon to perform more breast-conserving surgery, but the long-term results for breast tumor to recur in these patients are not yet available. At our hospital, a tumor larger than 30 mm is an indication for mastectomy. In general,only 20.6 % of all patients are suitable for neoadjuvant chemotherapy. Patients with lobular carcinoma or with tumors with an extensive ductal carcinoma in situ part will not benefit from such therapy. Tumor remission following neoadjuvant chemotherapy is of prognostic relevance. The rapid therapeutic effect of neoadjuvant therapy allows short-term evaluation of this treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:32:11