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Titolo:
Electromagnetic inverse solutions in anatomically constrained spherical head models
Autore:
Spinelli, L; Andino, SG; Lantz, G; Seeck, M; Michel, CM;
Indirizzi:
Univ Hosp Geneva, Dept Neurol, Functional Brain Mapping Lab, Neurol Clin, CH-1211 Geneva 14, Switzerland Univ Hosp Geneva Geneva Switzerland 14 n, CH-1211 Geneva 14, Switzerland Univ Lausanne Hosp, Presurg Epilepsy Evaluat Lab, Program Funct Neurol & Neurosurg, Geneva, Switzerland Univ Lausanne Hosp Geneva Switzerland & Neurosurg, Geneva, Switzerland Univ Lausanne Hosp, Presurg Epilepsy Evaluat Lab, Program Functional Neurol & Neurosurg, Lausanne, Switzerland Univ Lausanne Hosp Lausanne Switzerland eurosurg, Lausanne, Switzerland Univ Geneva, Plurifac Program Cognit Neurosci, Geneva, Switzerland Univ Geneva Geneva Switzerland ram Cognit Neurosci, Geneva, Switzerland
Titolo Testata:
BRAIN TOPOGRAPHY
fascicolo: 2, volume: 13, anno: 2000,
pagine: 115 - 125
SICI:
0896-0267(200024)13:2<115:EISIAC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
EEG SOURCE LOCALIZATION; LOCAL MESH REFINEMENT; DIPOLE LOCALIZATION; SCALP POTENTIALS; HUMAN BRAIN; MAGNETOENCEPHALOGRAPHY; GEOMETRIES;
Keywords:
EEG; MRI; co-registration; spline; source localization; head model;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Michel, CM Univ Hosp Geneva, Dept Neurol, Functional Brain Mapping Lab, Neurol Clin, 24 Rue Micheli du Crest, CH-1211 Geneva 14, Switzerland Univ Hosp Geneva 24 Rue Micheli du Crest Geneva Switzerland 14
Citazione:
L. Spinelli et al., "Electromagnetic inverse solutions in anatomically constrained spherical head models", BRAIN TOPOG, 13(2), 2000, pp. 115-125

Abstract

Two classes of functional neuroimaging methods exist: hemodynamic techniques such as PET and fMRI, and electromagnetic techniques such as EEG/ERP andMEG. In order to fusion these images with anatomical information, co-registration with volumetric MRT is needed. While such co-registration techniques are well established for hemodynamic images, additional steps are needed for electromagnetic recordings, because the activity is only recorded on the scalp surface and inverse solutions based on specific head models have tobe used to estimate the 3-dimensional current distribution. To date most of the experimental and clinical studies use multi-shell concentric sphere models of the head, solve the inverse problem on this simplistic model, and then co-register the solution with the MRT using homogeneous transform operations. Contrary to this standard method, we here propose to map the MRI tothe spherical system by defining transformation operations that transform the MRI to a best-fitting sphere. Once done so, the solution points are defined in the cerebral tissue of this deformed MRI and the lead field for thedistributed linear inverse solutions is calculated for this solution space. The method, that we call SMAC (Spherical Model with Anatomical Constrains) is tested with simulations, as well as with the following real data: 1) estimation of the sources of visual evoked potentials to unilateral stimulation from data averaged over subjects, and 2) localization of interictal discharges of two epileptic patients, one with a temporal, the other with an occipital focus, both confirmed by seizure freedom after resection of the epileptogenic region.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 08:44:36