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Titolo:
Tracer kinetic modeling in nuclear cardiology
Autore:
DeGrado, TR; Bergmann, SR; Ng, CK; Raffel, DM;
Indirizzi:
Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA Duke Univ Durham NCUSA 27710 Med Ctr, Dept Radiol, Durham, NC 27710 USA Columbia Univ, Dept Med, Div Cardiol, New York, NY USA Columbia Univ New York NY USA v, Dept Med, Div Cardiol, New York, NY USA Yale Univ, Dept Diagnost Radiol, New Haven, CT 06510 USA Yale Univ New Haven CT USA 06510 Diagnost Radiol, New Haven, CT 06510 USA Univ Michigan, Dept Radiol, Detroit, MI USA Univ Michigan Detroit MI USAUniv Michigan, Dept Radiol, Detroit, MI USA
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 6, volume: 7, anno: 2000,
pagine: 686 - 700
SICI:
1071-3581(200011/12)7:6<686:TKMINC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION TOMOGRAPHY; MYOCARDIAL BLOOD-FLOW; CORONARY-ARTERY DISEASE; GLUCOSE METABOLIC-RATE; FATTY-ACID METABOLISM; NORMAL HUMAN HEARTS; OXYGEN-CONSUMPTION; NONINVASIVE QUANTIFICATION; LUMPED CONSTANT; N-13 AMMONIA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
108
Recensione:
Indirizzi per estratti:
Indirizzo: DeGrado, TR Duke Univ, Med Ctr, Dept Radiol, Box 3949, Durham, NC 27710 USA Duke Univ Box 3949 Durham NC USA 27710 9, Durham, NC 27710 USA
Citazione:
T.R. DeGrado et al., "Tracer kinetic modeling in nuclear cardiology", J NUCL CARD, 7(6), 2000, pp. 686-700

Abstract

The introduction of tracer kinetic modeling techniques in conjunction withnuclear imaging has allowed the assessment of physiologic processes in themyocardium in a noninvasive and quantitative manner. Alongside the development of novel radiopharmaceuticals for both positron emission tomography and single photon emission computed tomography is the clarification of their pharmacology, pharmacokinetics, and modeling strategies for assessment of physiologic rates from imaging data. Image analysis and tracer kinetic modeling techniques used in nuclear cardiology must address unique considerations related to the heart. The most commonly used tracers and modeling techniques are presently discussed, with particular attention given to methods that allow absolute quantitation of physiologic processes. The applications ofthese techniques are obvious in research protocols and may find more use in future clinical studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:02:22