Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Endothelial adherens junctions
Autore:
Petzelbauer, P; Halama, T; Groger, M;
Indirizzi:
Univ Vienna, Sch Med, Dept Dermatol, Div Gen Dermatol, A-1090 Vienna, Austria Univ Vienna Vienna Austria A-1090 v Gen Dermatol, A-1090 Vienna, Austria
Titolo Testata:
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS
fascicolo: 1, volume: 5, anno: 2000,
pagine: 10 - 13
SICI:
1087-0024(200012)5:1<10:EAJ>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-ADHESION MOLECULE-1; PROTEIN-TYROSINE-PHOSPHATASE; CADHERIN-CATENIN COMPLEX; COLON-CARCINOMA CELLS; BETA-CATENIN; VE-CADHERIN; N-CADHERIN; SIGNAL-TRANSDUCTION; TUBE FORMATION; CYCLIN D1;
Keywords:
angiogenesis; beta-catenin; inflammation; PECAM-1; VE-cadherin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Petzelbauer, P Univ Vienna, Sch Med, Dept Dermatol, Div Gen Dermatol, Waehringer Guertel 18-20, A-1090 Vienna, Austria Univ Vienna Waehringer Guertel18-20 Vienna Austria A-1090
Citazione:
P. Petzelbauer et al., "Endothelial adherens junctions", J INV D SYM, 5(1), 2000, pp. 10-13

Abstract

The principle of the molecular organization of adherens junctions follows a uniform pattern, which is found in epithelial, muscular, neuroneal as well as in endothelial cells and is highly conserved among species. Transmembrane molecules of the cadherin family link to catenins, which anchor the adhesion plaque to the cytoskeleton. The kind of cadherin used in adherens junctions is cell-type specific, vascular endothelial (VE)-cadherin is specific for endothelial cells. The assembly and disassembly of the cadherin/catenin complex is dynamic and regulated by growth factors. The functional status of adherens junctions controls endothelial cell-to-cell adhesion, cell scattering, vessel morphogenesis and has intracellular signaling properties, thereby playing an important role in vasculogenesis and angiogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 14:17:30