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Titolo:
A prospective study of human papillomavirus (HPV) type 16 DNA detection bypolymerase chain reaction and its association with acquisition and persistence of other HPV types
Autore:
Liaw, KL; Hildesheim, A; Burk, RD; Gravitt, P; Wacholder, S; Manos, MM; Scott, DR; Sherman, ME; Kurman, RJ; Glass, AG; Anderson, SM; Schiffman, M;
Indirizzi:
Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15213 USA Univ PittsburghPittsburgh PA USA 15213 idemiol, Pittsburgh, PA 15213 USA NCI, Dept Canc Epidemiol & Genet, Bethesda, MD 20892 USA NCI Bethesda MD USA 20892 Canc Epidemiol & Genet, Bethesda, MD 20892 USA Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA Johns HopkinsMed Inst Baltimore MD USA 21205 ol, Baltimore, MD 21205 USA Albert Einstein Coll Med, Dept Pediat, Bronx, NY 10467 USA Albert EinsteinColl Med Bronx NY USA 10467 t Pediat, Bronx, NY 10467 USA Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10467 USA Albert Einstein Coll Med Bronx NY USA 10467 Immunol, Bronx, NY 10467 USA Albert Einstein Coll Med, Dept Epidemiol & Social Med, Bronx, NY 10467 USAAlbert Einstein Coll Med Bronx NY USA 10467 cial Med, Bronx, NY 10467 USA Kaiser Fdn Res Inst, Oakland, CA USA Kaiser Fdn Res Inst Oakland CA USAKaiser Fdn Res Inst, Oakland, CA USA Kaiser Permanente Ctr Hlth Res, Portland, OR USA Kaiser Permanente Ctr Hlth Res Portland OR USA lth Res, Portland, OR USA Lab Corp Amer, Res Triangle Pk, NC USA Lab Corp Amer Res Triangle Pk NC USA Corp Amer, Res Triangle Pk, NC USA
Titolo Testata:
JOURNAL OF INFECTIOUS DISEASES
fascicolo: 1, volume: 183, anno: 2001,
pagine: 8 - 15
SICI:
0022-1899(20010101)183:1<8:APSOHP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYTOLOGICALLY NORMAL WOMEN; CERVICAL-CANCER; INFECTION; PARTICLES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Liaw, KL Univ Pittsburgh, Dept Epidemiol, 513 Parran Hall,130 De Soto St, Pittsburgh, PA 15213 USA Univ Pittsburgh 513 Parran Hall,130 De Soto St Pittsburgh PA USA 15213
Citazione:
K.L. Liaw et al., "A prospective study of human papillomavirus (HPV) type 16 DNA detection bypolymerase chain reaction and its association with acquisition and persistence of other HPV types", J INFEC DIS, 183(1), 2001, pp. 8-15

Abstract

Human papillomavirus (HPV)-16 causes about half the cases of cervical cancer worldwide and is the focus of HPV vaccine development efforts. Systematic data are lacking as to whether the prevention of HPV-16 could affect the equilibrium of infection with other HPV types and thus alter the predicted impact of vaccination on the occurrence of cervical neoplasia. Therefore, the associations of HPV-16 detection with subsequent acquisition of other HPV types and with the persistence of concomitantly detected HPV types were examined prospectively among 1124 initially cytologically normal women. Preexisting HPV-16 was generally associated with an increased risk for subsequent acquisition of other types. HPV-16 did not affect the persistence of concomitant infections, regardless of type. These findings suggest that the prevention or removal of HPV-16 is not likely to promote the risk of infection with other types, a theoretical concern with current vaccination efforts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 06:06:57