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Titolo:
Pain-related somatosensory evoked magnetic fields induced by controlled ballistic mechanical impacts
Autore:
Druschky, K; Lang, E; Hummel, C; Kaltenhauser, M; Kohlloffel, LUE; Neundorfer, B; Stefan, H;
Indirizzi:
Univ Erlangen Nurnberg, Dept Neurol, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany Univ Erlangen Nurnberg, Inst Physiol & Expt Pathophysiol, Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany Pathophysiol, Erlangen, Germany
Titolo Testata:
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
fascicolo: 6, volume: 17, anno: 2000,
pagine: 613 - 622
SICI:
0736-0258(200011)17:6<613:PSEMFI>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; EVENT-RELATED POTENTIALS; CO2-LASER STIMULATION; CEREBRAL POTENTIALS; CO2 STIMULATION; NASAL-MUCOSA; LOCALIZATION; RESPONSES; MAGNETOENCEPHALOGRAPHY; ACTIVATION;
Keywords:
pain; mechanical impact stimulation; magnetoencephalography; somatosensory evoked magnetic fields;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Druschky, K Univ Erlangen Nurnberg, Dept Neurol, D-91054 Erlangen, GermanyUniv Erlangen Nurnberg Erlangen Germany D-91054 gen, Germany
Citazione:
K. Druschky et al., "Pain-related somatosensory evoked magnetic fields induced by controlled ballistic mechanical impacts", J CL NEURPH, 17(6), 2000, pp. 613-622

Abstract

The purpose of this study was to investigate cortical processing of painful compared with tactile mechanical stimulation by means of magnetoencephalography (MEG) using the novel technique of mechanical impact loading. A light, hard projectile is accelerated pneumatically in a guiding barrel and elicits a brief sensation of pain when hitting the skin in free flight. Controllable noxious and innocuous impact velocities facilitate the generation ofdifferent, predetermined stimulus intensities. The authors applied painfulas well as tactile mechanical impacts to the dorsum of the second, third, and fourth digit of the nondominant hand. Pain-related somatosensory evokedmagnetic fields (SSEFs) were compared with those following tactile stimulation in seven healthy volunteers. Contralateral primary sensory cortical area activation was observed within the first 70 msec after tactile as well as painful stimulus intensities. Only painful impacts elicited SSEF responses assigned to the bilateral secondary sensory cortical regions and to the middle part of the contralateral cingulate gyrus, which were active at latency ranges of 55 to 155 msec and 90 to 220 msec respectively. Additional long-latency responses occurred in these cortical areas as long as 280 msec after painful stimulation in three subjects. In contrast to tactile stimulation, painful mechanical impacts elicited SSEF responses in cortical areas demonstrated to be involved in central pain processing by previous MEG and neuroimaging studies. Because of its similarity to natural noxious stimuli and the possibility of adjustable painful and tactile impact velocities, the technique of mechanical impact loading provides a useful method for the neurophysiologic evaluation of cortical pain perception.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 05:33:41