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Titolo:
Tir tyrosine phosphorylation and pedestal formation are delayed in enteropathogenic Escherichia coli sepZ :: TnphoA mutant 30-5-1(3)
Autore:
DeVinney, R; Nisan, I; Ruschkowski, S; Rosenshine, I; Finlay, BB;
Indirizzi:
Univ British Columbia, Biotechnol Lab, Vancouver, BC V6T 1Z3, Canada Univ British Columbia Vancouver BC Canada V6T 1Z3 ver, BC V6T 1Z3, Canada Hebrew Univ Jerusalem, Dept Mol Genet, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel Hebrew Univ Jerusalem, Dept Biotechnol, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel Hebrew Univ Jerusalem, Dept Clin Microbiol, IL-91120 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 -91120 Jerusalem, Israel
Titolo Testata:
INFECTION AND IMMUNITY
fascicolo: 1, volume: 69, anno: 2001,
pagine: 559 - 563
SICI:
0019-9567(200101)69:1<559:TTPAPF>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
HOST EPITHELIAL-CELLS; SIGNAL-TRANSDUCTION; ENTEROCYTE EFFACEMENT; PROTEIN TRANSLOCATION; PATHOGENICITY ISLAND; RECEPTOR; SECRETION; EPEC; RABBIT; LOCUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Finlay, BB Univ British Columbia, Biotechnol Lab, Vancouver, BC V6T 1Z3, Canada Univ British Columbia Vancouver BC Canada V6T 1Z3 1Z3, Canada
Citazione:
R. DeVinney et al., "Tir tyrosine phosphorylation and pedestal formation are delayed in enteropathogenic Escherichia coli sepZ :: TnphoA mutant 30-5-1(3)", INFEC IMMUN, 69(1), 2001, pp. 559-563

Abstract

Enteropathogenic Escherichia call (EPEC) strain 30-5-1(3) has been reported to form attaching and effacing (A/E) lesions without Tir tyrosine phosphorylation. In this study, we show that 30-5-1(3), which has a transposon insertion within the sepZ gene, forms wild-type A/E lesions including Tir tyrosine phosphorylation, but at a slower rate. A/E lesion formation by 30-5-1(3) occurs without detectable secretion of Tir or other EPEC Esp secreted proteins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/08/20 alle ore 23:27:12