Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Age at any birth is associated with breast cancer risk
Autore:
Wohlfahrt, J; Melbye, M;
Indirizzi:
Statens Serum Inst, Danish Epidemiol Sci Ctr, Dept Epidemiol Res, DK-2300 Copenhagen S, Denmark Statens Serum Inst Copenhagen Denmark S s, DK-2300 Copenhagen S, Denmark
Titolo Testata:
EPIDEMIOLOGY
fascicolo: 1, volume: 12, anno: 2001,
pagine: 68 - 73
SICI:
1044-3983(200101)12:1<68:AAABIA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
REPRODUCTIVE FACTORS; WOMEN; POPULATION; DELIVERY; PARITY; 1ST;
Keywords:
breast cancer risk; reproductive history; cohort study; population-based;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Melbye, M Statens Serum Inst, Danish Epidemiol Sci Ctr, Dept Epidemiol Res, Artillerivej 5, DK-2300 Copenhagen S, Denmark Statens Serum Inst Artillerivej 5 Copenhagen Denmark S Denmark
Citazione:
J. Wohlfahrt e M. Melbye, "Age at any birth is associated with breast cancer risk", EPIDEMIOLOG, 12(1), 2001, pp. 68-73

Abstract

The period before the first birth is traditionally viewed as particularly critical for a woman's breast cancer risk. Nonetheless, the importance of early timing of a woman's first compared with subsequent births is not well understood. In the present study we examine this question using a population-based cohort of 1.5 million Danish women born between 1935 and 1978, Between 1968 and 1994, 13,049 incident cases of breast cancer were identified in the Danish Cancer Registry. According to our results, a woman's breast cancer risk is related to her age at any of her births. The risk increase per5 year's increase in maternal age at first, second, third, and fourth birth was 9%, 7%, 5%, and 14%, respectively. For fifth and sixth births it was 5%. We observed a risk reduction after any birth occurring before 30 years of age (in uniparous women before 25 years of age). These effects were strongest more than 10 years after birth. Thus, our study shows that early timing of any additional birth induces an additional long-term reduction in maternal risk of breast cancer; that is, early reproductive years, rather thanjust the nulliparous years, constitute the critical period.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 02:45:50