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Titolo:
HIGH-DOSE METHYLPREDNISOLONE-INDUCED DRAMATIC MATURATION OF GRANULOCYTES IN IDIOPATHIC CHRONIC NEUTROPENIA
Autore:
YETGIN S; OZBEK N;
Indirizzi:
HACETTEPE UNIV,FAC MED,DEPT PEDIAT,HEMATOL UNIT TR-06100 ANKARA TURKEY
Titolo Testata:
Turkish Journal of Pediatrics
fascicolo: 2, volume: 39, anno: 1997,
pagine: 259 - 263
SICI:
0041-4301(1997)39:2<259:HMDMOG>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYELOID LEUKEMIC-CELLS; COLONY-STIMULATING-FACTOR; CONGENITAL NEUTROPENIA;
Keywords:
IDIOPATHIC CHRONIC NEUTROPENIA; HIGH-DOSE METHYLPREDNISOLONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
S. Yetgin e N. Ozbek, "HIGH-DOSE METHYLPREDNISOLONE-INDUCED DRAMATIC MATURATION OF GRANULOCYTES IN IDIOPATHIC CHRONIC NEUTROPENIA", Turkish Journal of Pediatrics, 39(2), 1997, pp. 259-263

Abstract

Idiopathic chronic neutropenia is characterized by a variable patternof age at the onset of neutropenia, neutrophil counts, maturational arrest at the promyelocyte/myelocyte stage in the bone marrow, and recurrent pyogenic infections without any underlying disease or drug administration. There have been reports of lack of response to conventional-dose steroid therapy, but in recent studies it has been shown that high-dose corticosteroids are effective in several neutropenic states. Here we report an apparent response to high-dose methylprednisolone in a patient with idiopathic chronic neutropenia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:42:40