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Titolo:
Functional imaging of conditioned aversive emotional responses in antisocial personality disorder
Autore:
Schneider, F; Habel, U; Kessler, C; Posse, S; Grodd, W; Muller-Gartner, HW;
Indirizzi:
Univ Dusseldorf, Dept Psychiat, D-40629 Dusseldorf, Germany Univ Dusseldorf Dusseldorf Germany D-40629 , D-40629 Dusseldorf, Germany KFA Julich GmbH, Res Ctr, Inst Med, D-5170 Julich, Germany KFA Julich GmbH Julich Germany D-5170 , Inst Med, D-5170 Julich, Germany Univ Tubingen, Dept Neuroradiol, D-7400 Tubingen, Germany Univ Tubingen Tubingen Germany D-7400 roradiol, D-7400 Tubingen, Germany Univ Dusseldorf, Dept Nucl Med, D-4000 Dusseldorf, Germany Univ Dusseldorf Dusseldorf Germany D-4000 ed, D-4000 Dusseldorf, Germany
Titolo Testata:
NEUROPSYCHOBIOLOGY
fascicolo: 4, volume: 42, anno: 2000,
pagine: 192 - 201
SICI:
0302-282X(2000)42:4<192:FIOCAE>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; HUMAN AMYGDALA ACTIVATION; BLOOD-FLOW; STARTLE REFLEX; PSYCHOPATHS; MODULATION; MECHANISMS; FMRI; PET;
Keywords:
functional magnetic resonance imaging; antisocial personality; classical conditioning; emotion; amygdala; dorsolateral prefrontal cortex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Schneider, F Univ Dusseldorf, Dept Psychiat, Berg Landstr 2, D-40629 Dusseldorf, Germany Univ Dusseldorf Berg Landstr 2 Dusseldorf Germany D-40629 ny
Citazione:
F. Schneider et al., "Functional imaging of conditioned aversive emotional responses in antisocial personality disorder", NEUROPSYCHB, 42(4), 2000, pp. 192-201

Abstract

Individuals with antisocial personality disorder (n = 12) and healthy controls (n = 12) were examined for cerebral regional activation involved in the processing of negative affect. A differential aversive classical conditioning paradigm was applied with odors as unconditioned stimuli and faces as conditioned stimuli. Functional magnetic resonance imaging (fMRI) based on echo-planar imaging was used while cerebral activity was studied during habituation, acquisition, and extinction. Individually defined cerebral regions were analyzed. Both groups indicated behavioral conditioning following subjective ratings of emotional valence to conditioned stimuli. Differential effects were found during acquisition in the amygdala and dorsolateral prefrontal cortex. Controls showed signal decreases, patients signal increases. These preliminary results revealed unexpected signal increases in cortical/subcortical areas of patients. The increases mayresult from an additional effort put in by these individuals to form negative emotional associations,a pattern of processing that may correspond to their characteristic deviant emotional behavior. Copyright (C) 2000 S. Karger AG, Basel.

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Documento generato il 24/01/20 alle ore 12:19:13