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Titolo:
BOVINE IMMUNODEFICIENCY VIRUS
Autore:
DAFFNER J; SCORTTI M;
Indirizzi:
UNIV NACL LITORAL,FAC AGRON & VET SANTA FE ARGENTINA
Titolo Testata:
Archivos de medicina veterinaria
fascicolo: 1, volume: 29, anno: 1997,
pagine: 5 - 11
SICI:
0301-732X(1997)29:1<5:BIV>2.0.ZU;2-#
Fonte:
ISI
Lingua:
SPA
Soggetto:
MULTIPLE RETROVIRAL INFECTIONS; MOLECULAR-CLONING; CATTLE; LENTIVIRUS; CALVES; GENE;
Keywords:
BIV; LYMPHADENOPATHY; BOVINE; REVIEW;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J. Daffner e M. Scortti, "BOVINE IMMUNODEFICIENCY VIRUS", Archivos de medicina veterinaria, 29(1), 1997, pp. 5-11

Abstract

At present, a considerable amount of knowledge has accumulated about the molecular biology of bovine immunodeficiency-like virus -BIV-. BIVhas the most complex genome of the nonprimate lentiviruses and contains a series of accessory genes that are used to positively regulate virus gene expression in a fashion similar to that exhibited by the primate lentiviruses. This similarity in BIV and primate lentivirus accessory gene function may help in efforts to elucidate the role of accessory genes in lentivirus replication and pathogenicity. BIV infection ofcattle does not produce acute clinical diseases in the absence of cofactors, and thus is typical of most other ungulate and simian lentiviruses with reduced pathogenicity, which have naturally evolved during virus-host adaptation. This finding contrasts with more acutely pathogenic lentiviruses, such as SIV pbj and MVV strain K1772. They have recently mutated to forms that induce a rapid clinical disease and a quickdeath for the host. In any event, bovine susceptibility to BIV disease may depend upon BIV strains, but also on bovine breeds and environmental factors. It thus will be important to determine the factors that regulate BIV expression and enhance pathogenicity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:44:24