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Titolo:
Hemispheric and gender-related differences in the gross morphology of the anterior cingulate/paracingulate cortex in normal volunteers: An MRI morphometric study
Autore:
Yucel, M; Stuart, GW; Maruff, P; Velakoulis, D; Crowe, SF; Savage, G; Pantelis, C;
Indirizzi:
Mental Hlth Res Inst, Appl Schizophrenia Div, Parkville, Vic 3052, Australia Mental Hlth Res Inst Parkville Vic Australia 3052 le, Vic 3052, Australia La Trobe Univ, Sch Psychol Sci, Bundoora, Vic 3083, Australia La Trobe Univ Bundoora Vic Australia 3083 , Bundoora, Vic 3083, Australia Univ Melbourne, Dept Psychiat, Cognit Neuropsychiat Unit, Melbourne, Vic 3052, Australia Univ Melbourne Melbourne Vic Australia 3052 elbourne, Vic 3052, Australia
Titolo Testata:
CEREBRAL CORTEX
fascicolo: 1, volume: 11, anno: 2001,
pagine: 17 - 25
SICI:
1047-3211(200101)11:1<17:HAGDIT>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN CEREBRAL-CORTEX; HUMAN-BRAIN; MONOZYGOTIC TWINS; CINGULATE CORTEX; FUNCTIONAL-ANATOMY; SULCAL VARIABILITY; CORPUS-CALLOSUM; PARACINGULATE; GYRIFICATION; ASYMMETRIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Yucel, M Mental Hlth Res Inst, Appl Schizophrenia Div, Parkville, Vic 3052, Australia Mental Hlth Res Inst Parkville Vic Australia 3052 052, Australia
Citazione:
M. Yucel et al., "Hemispheric and gender-related differences in the gross morphology of the anterior cingulate/paracingulate cortex in normal volunteers: An MRI morphometric study", CEREB CORT, 11(1), 2001, pp. 17-25

Abstract

The sulci and gyri found within the anterior cingulate (AC), and across the cerebrum generally, have been found to vary in location and complexity from one individual to the next, making it difficult to analyze imaging data accurately and systematically. In this study, we examined the nature of morphometric variance in the AC of the left and right cerebral hemispheres using high-resolution structural magnetic resonance imaging (MRI) acquired from 176 healthy volunteers. Depending on the presence of a paracingulate sulcus (PCS) and its antero posterior extent, three types of AG patterns were identified: 'prominent', 'present' and 'absent'. Hemispheric comparisons across the whole sample showed the PCS to be more commonly 'prominent' in the left hemisphere and more commonly 'absent' in the right hemisphere. There was a significant gender difference, such that males showed an asymmetric pattern characterized by increased fissurization of the left AC, while females showed greater symmetry, with less fissurization of the left AC. Overall cerebral morphology, namely hemispheric volume and hemispheric fissurization, were also measured and used as independent variables as well as covariates in the analyses in order to ascertain the specificity of the results regarding AC morphology. Results showed that cerebral volume for males was larger on the right than on the left while fissurization showed the reverse asymmetry of greater leftward fissurization. In contrast, females were symmetric in both respects. The findings regarding AC morphology could not be explained by differences in these overall cerebral measures or by differences in age and handedness within the population. The results suggest that in the normal male brain, there exist morphological asymmetries at both the global and local levels that are less apparent in the female brain. The findings have implications for future studies examining the organization, develop ment and functional anatomy of the AC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:49:13