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Titolo:
An abundance of tubulins
Autore:
Oakley, BR;
Indirizzi:
Ohio State Univ, Dept Mol Genet, Columbus, OH 43210 USA Ohio State Univ Columbus OH USA 43210 t Mol Genet, Columbus, OH 43210 USA
Titolo Testata:
TRENDS IN CELL BIOLOGY
fascicolo: 12, volume: 10, anno: 2000,
pagine: 537 - 542
SICI:
0962-8924(200012)10:12<537:AAOT>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICROTUBULE-ORGANIZING CENTER; MITOTIC SPINDLE FORMATION; YEAST GAMMA-TUBULIN; ASPERGILLUS-NIDULANS; CELL-CYCLE; SACCHAROMYCES-CEREVISIAE; FISSION YEAST; BETA-TUBULIN; POLE BODY; PROTEIN;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Oakley, BR Ohio State Univ, Dept Mol Genet, 484 W 12th Ave, Columbus, OH 43210 USA Ohio State Univ 484 W 12th Ave Columbus OH USA 43210 43210 USA
Citazione:
B.R. Oakley, "An abundance of tubulins", TR CELL BIO, 10(12), 2000, pp. 537-542

Abstract

Recent data have revealed that the tubulin superfamily of proteins is muchlarger than was thought previously. Six distinct families within the tubulin superfamily have been discovered and more might await discovery. alpha-,beta- and gamma -tubulins are ubiquitous in eukaryotes. alpha- and beta -tubulins are the major components of microtubules, and gamma -tubulin plays a major role in the nucleation of microtubule assembly. delta- and epsilon -tubulins are widespread but not ubiquitous, and zeta -tubulin has been found so far only in kinetoplastid protozoa. delta -Tubulin has art important role in flagellar assembly in Chlamydomonas, but its role in other organisms is just beginning to be investigated, as are the functions of the recently? discovered epsilon- and zeta -tubulins.

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Documento generato il 04/12/20 alle ore 09:08:10