Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Autonomic nervous system-controlled cardiac pacing: A comparison between intracardiac impedance signal and muscle sympathetic nerve activity
Autore:
Binggeli, C; Duru, F; Corti, R; Sudano, I; Spieker, LE; Turina, A; Westermann, P; Ostermeier, M; Rahn, M; Luscher, TF; Noll, G; Candinas, R;
Indirizzi:
Univ Zurich Hosp, Dept Cardiol, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland ETH Zurich, Commun Technol Lab, Zurich, Switzerland ETH Zurich Zurich Switzerland , Commun Technol Lab, Zurich, Switzerland Biotron SA, Bulach, Switzerland Biotron SA Bulach SwitzerlandBiotron SA, Bulach, Switzerland Univ Erlangen Nurnberg, Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany gen Nurnberg, Erlangen, Germany
Titolo Testata:
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
fascicolo: 11, volume: 23, anno: 2000,
parte:, 1
pagine: 1632 - 1637
SICI:
0147-8389(200011)23:11<1632:ANSCPA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLD PRESSOR TEST; VENOUS OXYGEN-SATURATION; HEART-FAILURE; EXERCISE; SENSOR; CONSTRICTION; PACEMAKERS; ACTIVATION; OUTFLOW; HUMANS;
Keywords:
sympathetic nervous system physiology; heart contractility; rate adaptive pacing; intracardiac pacing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Candinas, R Univ Zurich Hosp, Dept Cardiol, Ramistr 100, CH-8091 Zurich, Switzerland Univ Zurich Hosp Ramistr 100 Zurich Switzerland CH-8091 rland
Citazione:
C. Binggeli et al., "Autonomic nervous system-controlled cardiac pacing: A comparison between intracardiac impedance signal and muscle sympathetic nerve activity", PACE, 23(11), 2000, pp. 1632-1637

Abstract

A recently introduced rate responsive cardiac pacing system is based on information derived from the intracardiac impedance signal containing information on the inotropic state of the ventricle. This study compared the inotropic state index (ISI) with muscle sympathetic activity (MSA), both being modulated by the autonomic nervous system. Nine patients (66 +/- 3 years, mean +/- SEM) with Inos(2)DR pacemakers were included. Each patient was studied at rest and during cold presser test (CPT). Microneurography of the peroneal nerve was performed to measure MSA continuously, which was digitally stored along with continuous surface ECG and blood pressure. The intracardiac impedance signal was transmitted by the pacemaker and stored simultaneously. Linear correlation between ISI and MSA wets calculated for the period of the CPT. During CPT, mean systolic blood pressure increased from 122 +/- 4 to 249 +/- 6 mmHg (P < 0.0001), diastolic blood pressure increased from 74 +/- 8 to 86 +/- 4 mmHg (P = 0,02), and intrinsic heart rate increcrsed rom 69 +/- 7 to 75 +/- 7 beats/mill (P = 0.019). ISI increased by 21 +/- 7% (P = 0.018), MSA by 26 +/- 6% (P = 0.004). ISI and MSA were positively correlated during the CPT in eight of nine patients (R-2 = 0.86-0.99, P < 0.0001). Negative correlation was found in one patient (R-2 = 0.94). This study demonstrates parallel increases of the ISI and MSA during CPT. ISI and MSA showed a close linear relationship during provoked changes of sympathetic activity. These results provide further evidence that the sympathetic nervoussystem is responsible for the observed ISI changes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 09:49:12