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Titolo:
Gene therapy: Trials and tribulations
Autore:
Somia, N; Verma, IM;
Indirizzi:
Salk Inst Biol Studies, Genet Lab, La Jolla, CA 92037 USA Salk Inst Biol Studies La Jolla CA USA 92037 Lab, La Jolla, CA 92037 USA
Titolo Testata:
NATURE REVIEWS GENETICS
fascicolo: 2, volume: 1, anno: 2000,
pagine: 91 - 99
SICI:
1471-0056(200011)1:2<91:GTTAT>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADENOASSOCIATED VIRUS TYPE-2; RETROVIRAL VECTORS; MAMMALIAN-CELLS; NONDIVIDING CELLS; LENTIVIRAL VECTOR; EFFICIENT TRANSDUCTION; ADENOVIRAL VECTORS; CD34(+) CELLS; HIGH-LEVEL; IN-VIVO;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
77
Recensione:
Indirizzi per estratti:
Indirizzo: Verma, IM Salk Inst Biol Studies, Genet Lab, 10010 N Torrey Pines Rd, La Jolla, CA 92037 USA Salk Inst Biol Studies 10010 N Torrey Pines Rd La Jolla CA USA 92037
Citazione:
N. Somia e I.M. Verma, "Gene therapy: Trials and tribulations", NAT REV GEN, 1(2), 2000, pp. 91-99

Abstract

The art and science of gene therapy has received much attention of late. The tragic death of 18-year-old Jesse Gelsinger, a volunteer in a Phase I clinical trial, has overshadowed the successful treatment of three children suffering from a rare but fatal immunological disease. In the light of the success and tragedy, it is timely to consider the challenges faced by gene therapy - a novel form of molecular medicine that may be poised to have an important impact on human health in the new millennium.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 12:07:32