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Titolo:
Diagnosis of defects in the type 1 cytokine pathway
Autore:
Lammas, DA; Drysdale, P; Ben-Smith, A; Girdlestone, J; Edgar, D; Kumararatne, DS;
Indirizzi:
Univ Birmingham, MRC, Ctr Immune Regulat, Birmingham B15 2TT, W Midlands, England Univ Birmingham Birmingham W Midlands England B15 2TT W Midlands, England Royal Grp Hosp Trust, Dept Immunol, Belfast BT12 6BN, Antrim, North Ireland Royal Grp Hosp Trust Belfast Antrim North Ireland BT12 6BN North Ireland Birmingham Heartlands Hosp, Dept Immunol, Birmingham B9 5SS, W Midlands, England Birmingham Heartlands Hosp Birmingham W Midlands England B9 5SS , England
Titolo Testata:
MICROBES AND INFECTION
fascicolo: 13, volume: 2, anno: 2000,
pagine: 1567 - 1578
SICI:
1286-4579(200011)2:13<1567:DODITT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERFERON-GAMMA-RECEPTOR; CALMETTE-GUERIN INFECTION; MYCOBACTERIAL INFECTION; IFN-GAMMA; DEFICIENCY; SUSCEPTIBILITY; CHILD; INTERLEUKIN-12; TUBERCULOSIS; IMMUNITY;
Keywords:
interferon-gamma; interleukin-12; IFN-gamma-receptor; IL-12 recepcor; mycobacteria; salmonella; immunodeficiency;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Lammas, DA Univ Birmingham, MRC, Ctr Immune Regulat, Birmingham B15 2TT, WMidlands, England Univ Birmingham Birmingham W Midlands England B15 2TT England
Citazione:
D.A. Lammas et al., "Diagnosis of defects in the type 1 cytokine pathway", MICROBES IN, 2(13), 2000, pp. 1567-1578

Abstract

Patients with inherited defects in the interleukin-12 (IL-12)-dependent, 'high-output' interferon-gamma (IFN-gamma) pathway exhibit selective susceptibility to poorly pathogenic mycobacterial and salmonella infections. This review summarises the extended clinical spectrum seen in this group of patients and indicates a strategy for the identification of putative defects inthe type 1 cytokine pathway. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:34:41