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Titolo:
Magnesium sulfate and fetal plasma concentrations of epinephrine, norepinephrine, and vasopressin in response to acute hypoxemia in goats
Autore:
Sameshima, H; Tanaka, S; Kamitomo, M; Ikenoue, T; Sakamoto, H;
Indirizzi:
Miyazaki Med Coll, Dept Obstet & Gynecol, Miyazaki 8891692, Japan MiyazakiMed Coll Miyazaki Japan 8891692 ynecol, Miyazaki 8891692, Japan Miyazaki Med Coll, Perinatal Ctr, Miyazaki 88916, Japan Miyazaki Med CollMiyazaki Japan 88916 inatal Ctr, Miyazaki 88916, Japan Kagoshima City Hosp, Dept Obstet & Gynecol, Kagoshima, Japan Kagoshima City Hosp Kagoshima Japan Obstet & Gynecol, Kagoshima, Japan Kagoshima Univ, Dept Vet Med, Kagoshima 890, Japan Kagoshima Univ Kagoshima Japan 890 v, Dept Vet Med, Kagoshima 890, Japan
Titolo Testata:
JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
fascicolo: 6, volume: 7, anno: 2000,
pagine: 328 - 332
SICI:
1071-5576(200011/12)7:6<328:MSAFPC>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOVASCULAR-RESPONSES; OVINE FETUS; ADULT SHEEP; HEART-RATE; SECRETION; HYPOXIA; CATECHOLAMINES; RELEASE; LAMBS;
Keywords:
epinephrine; fetal goats; hypoxemia; magnesium sulfate; norepinephrine; vasopressin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Sameshima, H Miyazaki Med Coll, Dept Obstet & Gynecol, 5200 Kihara, Miyazaki 8891692, Japan Miyazaki Med Coll 5200 Kihara Miyazaki Japan 8891692 , Japan
Citazione:
H. Sameshima et al., "Magnesium sulfate and fetal plasma concentrations of epinephrine, norepinephrine, and vasopressin in response to acute hypoxemia in goats", J SOC GYN I, 7(6), 2000, pp. 328-332

Abstract

OBJECTIVE: We measured fetal plasma concentrations of epinephrine, norepinephrine, and vasopressin during acute hypoxemia in gents and tested whetherhypermagnesemia altered these endocrine responses. METHODS: Five chronically catheterized goat fetuses at 124-129 days' gestation were used, After 4 hours of infusion (magnesium or vehicle as controls), 30 minutes of hypoxemia was induced by infusing nitrogen gas though a maternal tracheal catheter. Fetal plasma concentrations of epinephrine, norepinephrine, and vasopressin were measured before and during hypoxemia. Both magnesium sulfate and vehicle infusions were performed in each animal. Repeated-measures analysis of variance (ANOVA) and two-way ANOVA with post hoc test were used to determine statistical significance. RESULTS: During hypoxemia, fetal Po-2 decreased significantly from 30 to 14 mmHg with no significant changes in fetal pH or Pco(2) in both groups. Fetal heart rate was reduced significantly by hypoxemia, but to a lesser extent in the magnesium group (change in decrease in fetal heart rate: 41 beatsper minute (bpm] in controls venus 26 bpm with magnesium). Mean blood pressure did not change significantly during hypoxemia in both groups. Fetal plasma concentrations of epinephrine, norepinephrine, and vasopressin significantly increased from the prehypoxemic values both with magnesium and in controls. There were no significant differences in these hormone concentrations between magnesium and the controls,CONCLUSION: Magnesium sulfate had no effect on fetal plasma concentrationsof vasopressin, epinephrine and norepinephrine during acute hypoxemia. (J Soc Gynecol Investig 2000; 7:328-32) Copyright (C) 2000 by the Society for Gynecologic Investigation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:02:24