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Titolo:
Development of a patient-specific dyspnoea questionnaire in motor neurone disease (MND): the MND dyspnoea rating scale (MDRS)
Autore:
Dougan, CF; Connell, CO; Thornton, E; Young, CA;
Indirizzi:
Walton Ctr Neurol & Neurosurg, Liverpool L9 7LJ, Merseyside, England Walton Ctr Neurol & Neurosurg Liverpool Merseyside England L9 7LJ England Univ Liverpool, Dept Psychol, Liverpool L69 3BX, Merseyside, England Univ Liverpool Liverpool Merseyside England L69 3BX , Merseyside, England
Titolo Testata:
JOURNAL OF THE NEUROLOGICAL SCIENCES
fascicolo: 1-2, volume: 180, anno: 2000,
pagine: 86 - 93
SICI:
0022-510X(20001101)180:1-2<86:DOAPDQ>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMYOTROPHIC-LATERAL-SCLEROSIS; OBSTRUCTIVE PULMONARY-DISEASE; CONTROLLED TRIAL; EXERCISE; SURVIVAL; ALS;
Keywords:
motor neurone disease; amyotrophic lateral sclerosis; dyspnoea; questionnaire; vital capacity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Young, CA Walton Ctr Neurol & Neurosurg, Lower Lane, Liverpool L9 7LJ, Merseyside, England Walton Ctr Neurol & Neurosurg Lower Lane Liverpool Merseyside England L9 7LJ
Citazione:
C.F. Dougan et al., "Development of a patient-specific dyspnoea questionnaire in motor neurone disease (MND): the MND dyspnoea rating scale (MDRS)", J NEUR SCI, 180(1-2), 2000, pp. 86-93

Abstract

Motor neurone disease (MND) is a progressive, unremitting and fatal disease. Respiratory dysfunction is common and a significant cause of morbidity. The relationship between subjective dyspnoea and objective measures of lungfunction have been unexplored in MND. Increasing interest in the specific treatment of respiratory symptoms in MND has highlighted the need for simple, reliable and valid measures to quantify the degree of dyspnoea in this condition. Several generic questionnaires have been developed to rate subjective breathlessness but are inappropriate for use in MND patients as they often assess dyspnoea by exercise-limitation. As yet, there are no publisheddisease-specific measures to assess dyspnoea in MND. In order to accurately and reproducibly measure the subjective experience of dyspnoea in this patient group, we have developed and validated a novel patient-specific dyspnoea questionnaire, the MND dyspnoea rating scale (MDRS). It comprises threedomains covering dyspnoea, emotion and mastery and is valid for use in MNDpatients at all stages of disease progression. In our cohort of 40 unselected patients with MND we have shown that the patients subjective experienceof dyspnoea is closely related to emotion and psychological control over the disease. Dyspnoea is not related to objective measures of lung function such as vital capacity, irrespective of limb or bulbar presentation. In conclusion, vital capacity, although useful prognostically, is only one aspectof respiratory function in MND. The MDRS is a reliable and valid tool to rate subjective dyspnoea in MND. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:33:45