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Titolo:
Interhemispheric interaction during childhood: II. Children with early-treated phenylketonuria
Autore:
Banich, MT; Passarotti, AM; White, DA; Nortz, MJ; Steiner, RD;
Indirizzi:
Univ Illinois, Beckman Inst, Dept Psychol, Urbana, IL 61801 USA Univ Illinois Urbana IL USA 61801 nst, Dept Psychol, Urbana, IL 61801 USA Univ Calif San Diego, Dept Cognit Sci, San Diego, CA 92103 USA Univ Calif San Diego San Diego CA USA 92103 Sci, San Diego, CA 92103 USA Washington Univ, Dept Psychol, St Louis, MO 63130 USA Washington Univ St Louis MO USA 63130 ept Psychol, St Louis, MO 63130 USA Oregon Hlth Sci Univ, Doernbecher Mem Hosp Children, Child Dev & Rehabil Ctr, Dept Pediat, Portland, OR 97201 USA Oregon Hlth Sci Univ Portland OR USA 97201 Pediat, Portland, OR 97201 USA Oregon Hlth Sci Univ, Doernbecher Mem Hosp Children, Child Dev & Rehabil Ctr, Dept Mol Genet, Portland, OR 97201 USA Oregon Hlth Sci Univ Portland OR USA 97201 Genet, Portland, OR 97201 USA
Titolo Testata:
DEVELOPMENTAL NEUROPSYCHOLOGY
fascicolo: 1, volume: 18, anno: 2000,
pagine: 53 - 71
SICI:
8756-5641(2000)18:1<53:IIDCIC>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUSTAINED ATTENTION; STROOP TASK; PHENYLALANINE; INTERFERENCE; HEMISPHERES; PERFORMANCE; DEFICITS; BRAIN; HYPERPHENYLALANINEMIA; CALLOSUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Banich, MT Univ Colorado, Dept Psychol, UCB 345, Boulder, CO 80309 USA Univ Colorado UCB 345 Boulder CO USA 80309 oulder, CO 80309 USA
Citazione:
M.T. Banich et al., "Interhemispheric interaction during childhood: II. Children with early-treated phenylketonuria", DEV NEUROPS, 18(1), 2000, pp. 53-71

Abstract

This study examined whether children with early-treated phenylketonuria (ETPKU) exhibited a disruption in communication between the hemispheres as a function of computational complexity (Banich & Belger, 1990; Belger & Banich, 1992, 1998) when compared to neurologically uncompromised children who were matched in age and IQ. This investigation was motivated by findings that phenylketonuria affects myelination of neurons, including those that makeup the corpus callosum, the main neural conduit for interhemispheric interaction. Children performed 2 tasks: a less complex physical-identity task and a more complex name-identity task. For both tasks, we compared performance on across-hemisphere trials, which require interhemispheric interaction,and on within-hemisphere trials, in which no hemispheric interaction is required. On the more complex name-identity task, children with ETPKU exhibited less of a benefit from across-hemisphere processing than did neurologically intact children. These results suggest that the interhemispheric interaction required to complete computationally complex tasks is compromised in children with ETPKU. Such an insufficiency may explain some of the attentional deficits observed in this group of children.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:25:39