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Titolo:
Zebrafish: a genetic approach in studying hematopoiesis
Autore:
Paw, BH; Zon, LI;
Indirizzi:
Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA Childrens Hosp Boston MA USA 02115 iv Hematol Oncol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Pediat Oncol, Boston, MA 02115 USA Dana FarberCanc Inst Boston MA USA 02115 iat Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 h Med, Dept Pediat, Boston, MA 02115 USA
Titolo Testata:
CURRENT OPINION IN HEMATOLOGY
fascicolo: 2, volume: 7, anno: 2000,
pagine: 79 - 84
SICI:
1065-6251(200003)7:2<79:ZAGAIS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEFINITIVE HEMATOPOIESIS; POSITIONAL CLONING; COMMON PRECURSOR; DANIO-RERIO; GLOBIN GENE; CELLS; MUTATIONS; CLOCHE; MOUSE; VASCULOGENESIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Zon, LI Childrens Hosp, Div Hematol Oncol, 320 Longwood Ave,Enders 7, Boston, MA 02115 USA Childrens Hosp 320 Longwood Ave,Enders 7 Boston MA USA 02115 5 USA
Citazione:
B.H. Paw e L.I. Zon, "Zebrafish: a genetic approach in studying hematopoiesis", CURR OPIN H, 7(2), 2000, pp. 79-84

Abstract

The zebrafish (Danio rerio) has emerged in recent years as an exciting animal model system for studying vertebrate organ development and, in particular, the development of the hematopoietic system. The combined advantages ofdevelopmental biology and genetic screens for mutations in zebrafish have provided insights into early events in hematopoiesis and identified severalgenes required for normal blood development in vertebrates. As a result ofthe large-scale mutagenesis screens for developmental mutants, several zebrafish mutants with defects in blood development have been recovered. This review discusses how these blood mutations in zebrafish have given new perspectives on hematopoietic development. (C) 2000 Lippincott Williams & Wilkins, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 13:29:32