Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Sperm adhesion molecules: Structure and function
Autore:
Jansen, S; Ekhlasi-Hundrieser, M; Topfer-Petersen, E;
Indirizzi:
Tierarztliches Inst Gottingen, D-37073 Gottingen, Germany Tierarztliches Inst Gottingen Gottingen Germany D-37073 ttingen, Germany Tierarztlichen Hsch Hannover, D-3000 Hannover, Germany Tierarztlichen HschHannover Hannover Germany D-3000 0 Hannover, Germany
Titolo Testata:
CELLS TISSUES ORGANS
fascicolo: 1-2, volume: 168, anno: 2001,
pagine: 82 - 92
SICI:
1422-6405(2001)168:1-2<82:SAMSAF>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
ZONA-PELLUCIDA GLYCOPROTEINS; FUCOSE-BINDING PROTEIN; IN-VITRO; OVIDUCTAL EPITHELIUM; ACROSIN GENE; TYROSINE PHOSPHORYLATION; MAMMALIAN FERTILIZATION; BOAR SPERMADHESINS; EGG INTERACTIONS; HAMSTER SPERM;
Keywords:
gamete binding; adhesion molecules; structure-function relationship;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
80
Recensione:
Indirizzi per estratti:
Indirizzo: Jansen, S Tierarztliches Inst Gottingen, Groner Landstr 2, D-37073 Gottingen, Germany Tierarztliches Inst Gottingen Groner Landstr 2 Gottingen Germany D-37073
Citazione:
S. Jansen et al., "Sperm adhesion molecules: Structure and function", CELLS T ORG, 168(1-2), 2001, pp. 82-92

Abstract

Fertilisation is a unique event in which the morphologically disparate gametes recognise, bind and fuse with each other. This event follows a highly regulated schedule of biochemical interactions, in which molecules are involved that mediate cell adhesion, signal transduction and the initiation of metabolic pathways. A plethora of molecules has been found on the male gamete and with regard to the different protein structures it is almost impossible to overlook the structures involved. Even more, carbohydrate structurescause an additional diversity with regard to the generation of surface structures. In this communication we try to elucidate the structures of proteins that have been known so far. We have focussed on spermadhesins, the zonadhesin, proacrosin and the PH-20 antigen. The variety of structures and also the common features a mong them as well as the presence of redundant systems are attributable to the evolutionary force of intraspecific sperm competition. This evolutionary force is assumed to be also responsible for the species selectivity observed in these adhesion molecules, which explains thepreferential binding of gametes in a homologous system. Copyright (C) 2001S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 15:39:00