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Titolo:
Fatty acid amide hydrolase substrate specificity
Autore:
Boger, DL; Fecik, RA; Patterson, JE; Miyauchi, H; Patricelli, MP; Cravatt, BF;
Indirizzi:
Scripps Clin & Res Fdn, Res Inst, Dept Chem, La Jolla, CA 92037 USA Scripps Clin & Res Fdn La Jolla CA USA 92037 Chem, La Jolla, CA 92037 USA Scripps Clin & Res Fdn, Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA Scripps Clin & Res Fdn La Jolla CA USA 92037 Biol, La Jolla, CA 92037 USA Scripps Clin & Res Fdn, Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA Scripps Clin & Res Fdn La Jolla CA USA 92037 Biol, La Jolla, CA 92037 USA
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 23, volume: 10, anno: 2000,
pagine: 2613 - 2616
SICI:
0960-894X(200012)10:23<2613:FAAHSS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAP JUNCTION COMMUNICATION; ACTIVE LIPID OLEAMIDE; ANANDAMIDE AMIDOHYDROLASE; BRAIN LIPIDS; INDUCE SLEEP; RECEPTOR; RAT; IDENTIFICATION; INHIBITION; BIOSYNTHESIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Boger, DL Scripps Clin & Res Fdn, Res Inst, Dept Chem, 10550 N Torrey Pines Rd, La Jolla, CA 92037 USA Scripps Clin & Res Fdn 10550 N Torrey Pines RdLa Jolla CA USA 92037
Citazione:
D.L. Boger et al., "Fatty acid amide hydrolase substrate specificity", BIOORG MED, 10(23), 2000, pp. 2613-2616

Abstract

Fatty acid amide hydrolase (FAAH), also referred to as oleamide hydrolase and anandamide amidohydrolase, is a serine hydrolase responsible for the degradation of endogenous oleamide and anandamide, fatty acid amides that function as chemical messengers. FAAH hydrolyzes a range of fatty acid amides,and the present study examines the relative rates of hydrolysis of a variety of natural and unnatural fatty acid primary amide substrates using pure recombinant rat FAAH. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 19:34:52