Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Neonatal alloimmune thrombocytopenia due to a rare anti-HPA-1b antibody
Autore:
Moosmann, P; Fauchere, JC; Halter, J; Binder, D; Schanz, U;
Indirizzi:
Univ Spital Zurich, Abt Hamatol DIM, CH-8091 Zurich, Switzerland Univ Spital Zurich Zurich Switzerland CH-8091 H-8091 Zurich, Switzerland Univ Spital Zurich, Klin Neonatol, Zurich, Switzerland Univ Spital ZurichZurich Switzerland lin Neonatol, Zurich, Switzerland
Titolo Testata:
SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT
fascicolo: 45, volume: 130, anno: 2000,
pagine: 1734 - 1737
SICI:
0036-7672(20001111)130:45<1734:NATDTA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
GER
Soggetto:
INCOMPATIBILITY; MANAGEMENT; MOTHER;
Keywords:
thrombocytes; platelet antigens; alloimmunthrombocytopenia; HPA-1b;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Schanz, U Univ Spital Zurich, Abt Hamatol DIM, Ramistr 100, CH-8091 Zurich, Switzerland Univ Spital Zurich Ramistr 100 Zurich Switzerland CH-8091 rland
Citazione:
P. Moosmann et al., "Neonatal alloimmune thrombocytopenia due to a rare anti-HPA-1b antibody", SCHW MED WO, 130(45), 2000, pp. 1734-1737

Abstract

Foetal and neonatal alloimmune thrombocytopenia is caused by transplacental transfer of antibodies directed against platelet antigens and affects approximately 1 in 1000-2500 neonates. Clinically relevant complications are the intracranial haemorrhages that occur in 10-20% of cases. 20 platelet antigen systems are currently known. However, immunisation is most frequently seen against two of these (HPA-1a and HPA-Sb). Treatment options include transfusion of compatible or, if these are not available while urgently needed, random donor platelets, intravenous immunoglobulin, and steroids. We report on a case of neonatal alloimmune thrombocytopenia, due to an anti-HPA-1b antibody in the third pregnancy of a 31-year-old Caucasoid woman. The infant was treated with repented maternal and random donor platelet transfusions and with a single dose of intravenous immunoglobulin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 09:33:51