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Titolo:
Novel human herpesviruses and related diseases.
Autore:
Agut, H; Fillet, AM; Calvez, V; Gautheret-Dejean, A;
Indirizzi:
Grp Hosp Pitie Salpetriere, UPRES EA 2387, CERVI, Virol Lab, F-75651 Paris13, France Grp Hosp Pitie Salpetriere Paris France 13 Lab, F-75651 Paris13, France
Titolo Testata:
MEDECINE ET MALADIES INFECTIEUSES
fascicolo: 10, volume: 30, anno: 2000,
pagine: 621 - 629
SICI:
0399-077X(200010)30:10<621:NHHARD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
FRE
Soggetto:
SARCOMA-ASSOCIATED HERPESVIRUS; MULTICENTRIC CASTLEMANS-DISEASE; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; POLYMERASE CHAIN-REACTION; KAPOSIS-SARCOMA; DNA-SEQUENCES; SEXUAL TRANSMISSION; NUCLEOTIDE-SEQUENCE; MONONUCLEAR-CELLS; PERIPHERAL-BLOOD;
Keywords:
B-lymphocytes; Exanthem subitum; herpesvirus; Kaposi's sarcoma; T-lymphocytes;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Agut, H Grp Hosp Pitie Salpetriere, UPRES EA 2387, CERVI, Virol Lab, 83 Blvd Hop, F-75651 Paris 13, France Grp Hosp Pitie Salpetriere 83 Blvd Hop Paris France 13 13, France
Citazione:
H. Agut et al., "Novel human herpesviruses and related diseases.", MED MAL INF, 30(10), 2000, pp. 621-629

Abstract

Three new human herpesviruses have been discovered recently: human herpesvirus 6 (HHV-6), human herpesvirus 7 (HHV-7), human herpesvirus 8 (HHV-8). HHV-6 and HHV-7 were identified after their isolation from blood lymphocyte cultures; HHV-8 was first detected by means of a specific molecular biologyapproach in the search for the etiologic agent of Kaposi's sarcoma. The three viruses infect lymphocytes, T-cells in the case of HHV-6 and HHV-7, B-cells in the case of HHV-8 They also infect endothelial and epithelial cells. Human infection with HHV-6 and HHV-7 is ubiquitous and widespread while the frequency of HHV-8 infection is increasing from Northern Europe to the center of Africa. Polymerase chain reaction is the most common detection method for these three viruses in human samples. HHV-6 is the causative agent of exanthem subitum and opportunistic infections. The pathogenicity of HHV-7 seems to be weak. HHV-8 is strongly associated with three lymphoproliferative diseases: Kaposi's sarcoma, Castleman's disease and primary effusion lymphomas. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 09:00:33