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Titolo:
Intact myelinated fibres in biopsies of ventral spinal roots after preganglionic traction injury to the brachial plexus. A proof that Sherrington's 'wrong way afferents" exist in man?
Autore:
Schenker, M; Birch, R;
Indirizzi:
Royal Natl Orthopaed Hosp, Peripheral Nerve Injury Unit, Stanmore HA7 4LP,Middx, England Royal Natl Orthopaed Hosp Stanmore Middx England HA7 4LP P,Middx, England
Titolo Testata:
JOURNAL OF ANATOMY
, volume: 197, anno: 2000,
parte:, 3
pagine: 383 - 391
SICI:
0021-8782(200010)197:<383:IMFIBO>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERIPHERAL-NERVE REGENERATION; UNMYELINATED AXONS; PAIN;
Keywords:
brachial plexus injury; ventral root afferents;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Birch, R Royal Natl Orthopaed Hosp, Peripheral Nerve Injury Unit, BrockleyHill, Stanmore HA7 4LP, Middx, England Royal Natl Orthopaed Hosp Brockley Hill Stanmore Middx England HA7 4LP
Citazione:
M. Schenker e R. Birch, "Intact myelinated fibres in biopsies of ventral spinal roots after preganglionic traction injury to the brachial plexus. A proof that Sherrington's 'wrong way afferents" exist in man?", J ANAT, 197, 2000, pp. 383-391

Abstract

Bell-Magendie's law of separation of spinal function states that afferent and efferent fibres join the spinal cord separately in ventral and dorsal spinal nerve roots. For over 100 years there have been reports that challenge the exclusiveness of this law in mammals; very few studies have referred to man. We conducted a prospective morphological study in patients with preganglionic traction injuries of the brachial plexus to address this question. Avulsed ventral and dorsal roots were examined after variable intervals from the injury for histological anti ultrastructural evidence for myelinated afferent fibres entering the cord via the ventral roots. Intact myelinated fibres were found in all ventral root specimens, but the majority of fibres in later biopsies are regenerative. A small number of fibres could be demonstrated that are likely to be 'wrong way ventral afferents'. Their number is falsely low due to wallerian degeneration of dorsal and ventral efferents following the mechanical and ischaemic effects of traction injury. Ourfindings are the first morphological evidence in human material that Bell-Magendie's law might not entirely be correct and they underline the difficulties in comparing traumatic with experimental rhizotomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 17:10:10