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Titolo:
Phylogenetic analysis of a retroposon family as represented on the human Xchromosome
Autore:
Kim, HS; Hyun, BH; Choi, JY; Crow, TJ;
Indirizzi:
Pusan Natl Univ, Coll Nat Sci, Div Biol Sci, Pusan 609735, South Korea Pusan Natl Univ Pusan South Korea 609735 Sci, Pusan 609735, South Korea Korea Res Inst Biosci & Biotechnol, Genet Resources Ctr, Taejon, South Korea Korea Res Inst Biosci & Biotechnol Taejon South Korea ejon, South Korea Univ Oxford, Warneford Hosp, Dept Psychiat, POWIC, Oxford OX1 2JD, EnglandUniv Oxford Oxford England OX1 2JD chiat, POWIC, Oxford OX1 2JD, England
Titolo Testata:
GENES & GENETIC SYSTEMS
fascicolo: 4, volume: 75, anno: 2000,
pagine: 197 - 202
SICI:
1341-7568(200008)75:4<197:PAOARF>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
HERV-K; EUKARYOTIC GENOME; SEXUAL SELECTION; WORLD MONKEYS; HOMO-SAPIENS; SPECIATION; EVOLUTION; ELEMENTS; SEQUENCE; GENES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, HS Pusan Natl Univ, Coll Nat Sci, Div Biol Sci, Pusan 609735, South Korea Pusan Natl Univ Pusan South Korea 609735 san 609735, South Korea
Citazione:
H.S. Kim et al., "Phylogenetic analysis of a retroposon family as represented on the human Xchromosome", GENE GEN SY, 75(4), 2000, pp. 197-202

Abstract

SINE-R elements constitute a class of retroposons derived from the long terminal repeat (LTR) of the human endogenous retrovirus HERV-K family that are present in hominoid primates and active in the human genome. In an investigation of the X chromosome, we identified twenty-five SINE-R elements with between 89.6 and 97.7% homology with the SINE-R.C2 element that is human specific, originally identified in the gene for the C2 component of complement. SINE-R.C2 and a sequence HS307 that we previously identified in a region of Xq21.3 that has a recently created homology with a 4 Mb block in Yp11.2 are amongst the group of elements that have diverged furthest from the parent HERV-K10 sequence. The sequences on the X chromosome resemble those that we previously described on chromosomes 7 and 17 and the Y chromosome, with a similar range of variation. Phylogenetic analysis from the retroposonfamily including those of African great apes using the neighbor-joining method suggests that the SINE-R retroposon family have evolved independently during primate evolution. Further investigation of SINE-R elements on the sex chromosomes, particularly in recently created regions of X-Y homology, may cast light on the timing of the retroposition process and its possible relevance to recent evolutionary change.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 15:05:41