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Titolo:
Sialomucin complex (rMuc4) expression during development of the rat cornea
Autore:
Hu, YJ; Carvajal, ME; Carraway, KL;
Indirizzi:
Univ Miami, Sch Med, Dept Cell Biol & Anat, Miami, FL 33101 USA Univ Miami Miami FL USA 33101 Dept Cell Biol & Anat, Miami, FL 33101 USA Univ Miami, Sch Med, Dept Biochem & Mol Biol, Miami, FL 33101 USA Univ Miami Miami FL USA 33101 ept Biochem & Mol Biol, Miami, FL 33101 USA
Titolo Testata:
CURRENT EYE RESEARCH
fascicolo: 4, volume: 21, anno: 2000,
pagine: 820 - 823
SICI:
0271-3683(2000)21:4<820:SC(EDD>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAMMARY ADENOCARCINOMA CELLS; OCULAR SURFACE; MUCIN GENES; PROTECTION; COMPONENT; TRACT; MODEL;
Keywords:
corneal epithelium; Muc4; sialomucin complex; rat; development;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Carvajal, ME Univ Miami, Sch Med, Dept Cell Biol & Anat, POB 016960, Miami, FL 33101 USA Univ Miami POB 016960 Miami FL USA 33101 Miami, FL 33101 USA
Citazione:
Y.J. Hu et al., "Sialomucin complex (rMuc4) expression during development of the rat cornea", CURR EYE R, 21(4), 2000, pp. 820-823

Abstract

Purpose. To determine changes in sialomucin complex (SMC, rat Muc4) expression in rat ocular surface tissue during development from birth to adult. Methods. Immunoblot and immunocytochemical analyses were performed on isolated corneal tissue and rat eyes, respectively, from animals at days 1, 9 and 15 after birth. Adult animals were used for comparison. Results. SMC was detected by immunoblotting at all ages (day 1-adult) and increased into adulthood. Immunocytochemical localization also showed steadily increasing amounts of SMC to adulthood. The SMC was located at the apical surface of the corneal epithelium and in the superficial layers of the stratified corneal epithelium. Conclusions. SMC at the corneal surfaces steadily increases during development to adulthood, but does not exhibit a marked transition in expression at the time of eye-opening.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 07:10:21