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Titolo:
Brain-stem auditory evoked potentials in children with perinatal encephalopathies
Autore:
Romero, G; Mandujano, M; Mendez, I; Sanchez, C;
Indirizzi:
Univ Autonoma Metropolitana Xochimilco, Maestria Rehabil Neurol, Mexico City 04960, DF, Mexico Univ Autonoma Metropolitana Xochimilco Mexico City DFMexico 04960 Mexico Univ Nacl Autonoma Mexico, IIMAS, Mexico City 04510, DF, Mexico Univ Nacl Autonoma Mexico Mexico City DF Mexico 04510 y 04510, DF, Mexico Inst Nacl Pediat, Lab Seguimiento Neurodesarrollo, Mexico City 04530, DF, Mexico Inst Nacl Pediat Mexico City DF Mexico 04530 exico City 04530, DF, Mexico
Titolo Testata:
CLINICAL NEUROPHYSIOLOGY
fascicolo: 11, volume: 111, anno: 2000,
pagine: 1901 - 1906
SICI:
1388-2457(200011)111:11<1901:BAEPIC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTENSIVE-CARE UNIT; PREMATURE-INFANTS; PREDICTIVE VALUE; PRETERM INFANTS; IMPAIRMENT; RESPONSES; TERM;
Keywords:
brain-stem auditory evoked potential; brain damage; neurological sequela; risk factor; principal component analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Romero, G Univ Autonoma Metropolitana Xochimilco, Maestria Rehabil Neurol,Calz Hueso 1100,Col Villa Quietud, Mexico City 04960, DF, Mexico Univ Autonoma Metropolitana Xochimilco Calz Hueso 1100,Col Villa Quietud Mexico CityDF Mexico 04960
Citazione:
G. Romero et al., "Brain-stem auditory evoked potentials in children with perinatal encephalopathies", CLIN NEU, 111(11), 2000, pp. 1901-1906

Abstract

Objective: We sought to describe if neurological damage, in terms of brainlesions, syndrome and syndrome severity led to abnormalities in the brain-stem auditory evoked potentials (BAEPs) in order to provide a profile of children that could be used as an indicator of subsequent neurological sequelae. We analyzed the BAEPs from a group of children having prior evidence ofneurological damage and determined the presence of neurological sequelae when the subjects were 3 years old. Methods: Brain-stem auditory evoked potentials (BAEPs) were carried out ina group of 154 children with perinatal neurological damage. The children were classified with neurofunctional (clinical and EEG alterations) or organic and neurofunctional brain disease (clinical, EEG and image alteration) and were all followed from the first month of life and serially for 3 years. We used principal component analysis (PCA), clustered analysis and linear correlation to determine association between BAEPs, risk factors and futuresequelae. Results: Latencies of BAEPs decreased significantly with age, and the timeof conduction was modified by the presence of neurological damage. All statistical analyses suggested positive and significant associations between risk factors (trophism and condition at birth), and the latencies of waves I, III and V as well as with IPL III-V (interpeak latency) and I-V. PCA showed that IPL I-III was also positively associated with condition at birth, severity of the neurological syndrome and encephalopathy. In addition, we found that the presence and type of sequela reflected changes in the latencies of the waves, as well as IPLs, primarily those of IPL I-Ill. Conclusions: Our results suggest that statistical methods are often neededto analyze neurological damage. The relation between BAEPs, risk factors and neurological sequelae allowed us to obtain a profile of children, which can be then used as an aid in the prognosis of children having a risk of developing neurological sequelae. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:29:08