Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Quantitative analysis of fushi tarazu factor 1 homolog messenger ribonucleic acids in the pituitary of salmon at different prespawning stages
Autore:
Higa, M; Kanda, H; Kitahashi, T; Ito, M; Shiba, T; Ando, H;
Indirizzi:
Hokkaido Univ, Grad Sch Sci, Div Biol Sci, Sapporo, Hokkaido 0600810, Japan Hokkaido Univ Sapporo Hokkaido Japan 0600810 oro, Hokkaido 0600810, Japan Kitasato Univ, Sch Sci, Dept Biosci, Sagamihara, Kanagawa 2288555, Japan Kitasato Univ Sagamihara Kanagawa Japan 2288555 , Kanagawa 2288555, Japan
Titolo Testata:
BIOLOGY OF REPRODUCTION
fascicolo: 6, volume: 63, anno: 2000,
pagine: 1756 - 1763
SICI:
0006-3363(200012)63:6<1756:QAOFTF>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
STEROIDOGENIC FACTOR-I; GONADOTROPIN-RELEASING-HORMONE; ORPHAN NUCLEAR RECEPTOR; GROWTH-RESPONSE PROTEIN-1; MATURING SOCKEYE-SALMON; BETA-SUBUNIT PROMOTER; LUTEINIZING-HORMONE; GENE-EXPRESSION; CHUM SALMON; GONADAL DEVELOPMENT;
Keywords:
anterior pituitary; FSH; gene regulation; GnRH; LH; seasonal reproduction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Ando, H Hokkaido Univ, Grad Sch Sci, Div Biol Sci, Sapporo, Hokkaido 0600810, Japan Hokkaido Univ Sapporo Hokkaido Japan 0600810 kaido 0600810, Japan
Citazione:
M. Higa et al., "Quantitative analysis of fushi tarazu factor 1 homolog messenger ribonucleic acids in the pituitary of salmon at different prespawning stages", BIOL REPROD, 63(6), 2000, pp. 1756-1763

Abstract

Steroidogenic factor 1 (SF-1) or Ad4BP is a member of the fushi tarazu factor 1 (FTZ-F1) family and an orphan nuclear receptor that plays an important role in the hypothalamus-pituitary-gonadal axis and the adrenal cortex. Although its critical role in the differentiation of adrenals, gonads, and pituitary gonadotropes has been well demonstrated, regulatory function of SF-1 during sexual maturation is yet to be examined. To investigate the potential role of SF-1 in sexual maturation, expression of two salmon FTZ-F1 homolog genes, sFF1-I and sFF1-II, was examined in the pituitaries of chum andsockeye salmons, using specific and sensitive RNase protection assays. Only sFF1-I mRNA was found in the pituitary and other organs, such as the ovary, spleen, liver, brain, and skeletal muscle. In chum salmon during upstream migration from the bay to the hatchery, the level of sFF1-I mRNA in the male fish was increased on the midway in the river, where the levels of gonadotropin alpha- and II beta -subunit mRNAs were increased. In maturing sockeye salmon, the expression of the sFF1-I gene was elevated in the mature male fish, but the administration of CnRH analog did not further enhance the expression. These results indicate that sFF1-I gene expression in the pituitary is upregulated in maturing salmon, and this upregulation may not depend on GnRH.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 07:10:00