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Titolo:
Cessation of cerebral hemorrhage recurrence associated with corticosteroidtreatment in a patient with cerebral amyloid angiopathy
Autore:
Hoshi, K; Yoshida, K; Nakamura, A; Tada, T; Tamaoka, A; Ikeda, S;
Indirizzi:
Shinshu Univ, Sch Med, Dept Med Neurol, Matsumoto, Nagano 3908621, Japan Shinshu Univ Matsumoto Nagano Japan 3908621 sumoto, Nagano 3908621, Japan Shinshu Univ, Sch Med, Dept Neurosurg, Matsumoto, Nagano 3908621, Japan Shinshu Univ Matsumoto Nagano Japan 3908621 sumoto, Nagano 3908621, Japan Univ Tsukuba, Inst Clin Med, Dept Neurol, Ibaraki, Osaka 3058575, Japan Univ Tsukuba Ibaraki Osaka Japan 3058575 l, Ibaraki, Osaka 3058575, Japan
Titolo Testata:
AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION
fascicolo: 4, volume: 7, anno: 2000,
pagine: 284 - 288
SICI:
1350-6129(200012)7:4<284:COCHRA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; GIANT-CELL ARTERITIS; GRANULOMATOUS-ANGIITIS; CEREBROSPINAL-FLUID; ALZHEIMERS-DISEASE; BETA-PROTEIN; CYSTATIN-C; DIAGNOSIS;
Keywords:
cerebral amyloid angiopathy; cerebral hemorrhage; amyloid; beta protein; corticosteroid;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Ikeda, S Shinshu Univ, Sch Med, Dept Med Neurol, Matsumoto, Nagano 3908621, Japan Shinshu Univ Matsumoto Nagano Japan 3908621 agano 3908621, Japan
Citazione:
K. Hoshi et al., "Cessation of cerebral hemorrhage recurrence associated with corticosteroidtreatment in a patient with cerebral amyloid angiopathy", AMYLOID, 7(4), 2000, pp. 284-288

Abstract

We report the case of a 65 year old female patient with biopsy-proven cerebral amyloid angiopathy (CAA). She experienced intracerebral hemorrhages 4 times during 23 days but thee serous strokes did not recur after corticosteroid therapy was started and her condition greatly improved. Since high titers of antinuclear antibodies and elevated erythrocyte sedimentation rate were found in her serum, she may have an inflammatory disorder involving amyloid-laden cerebral vessels. This is the first report showing the usefulness of corticosteroid for the treatment of CAA-related cerebral hemorrhages. Additionally, the concentrations of A beta 40 and A beta 42 in the CSF of this patient decreased rapidly after the use of corticosteroid, and ultimately fell far below normal values.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 08:42:07