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Titolo:
Combined perfusion- and diffusion-weighted MR imaging in acute ischemic stroke during the 1st week: A longitudinal study
Autore:
Karonen, JO; Liu, YW; Vanninen, RL; Ostergaard, L; Partanen, PLK; Vainio, PA; Vanninen, EJ; Nuutinen, J; Roivainen, R; Soimakallio, S; Kuikka, IT; Aronen, HJ;
Indirizzi:
Kuopio Univ Hosp, Dept Clin Radiol, FIN-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FIN-70210 iol, FIN-70210 Kuopio, Finland Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, FIN-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland FIN-70210 Med, FIN-70210 Kuopio, Finland Aarhus Univ Hosp, Dept Neuroradiol, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 oradiol, DK-8000 Aarhus, Denmark Haage Neurol Res Ctr, Helsinki, Finland Haage Neurol Res Ctr Helsinki Finland Neurol Res Ctr, Helsinki, Finland Niuvanniemi Hosp, Dept Forens Psychiat, Kuopio, Finland Niuvanniemi Hosp Kuopio Finland , Dept Forens Psychiat, Kuopio, Finland Univ Helsinki, Cent Hosp, Dept Radiol, Helsinki, Finland Univ Helsinki Helsinki Finland ent Hosp, Dept Radiol, Helsinki, Finland
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 217, anno: 2000,
pagine: 886 - 894
SICI:
0033-8419(200012)217:3<886:CPADMI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; HIGH-RESOLUTION MEASUREMENT; TRACER BOLUS PASSAGES; HYPERACUTE STROKE; MAGNETIC-SUSCEPTIBILITY; THERAPY; PENUMBRA; CONTRAST; VOLUME; ECASS;
Keywords:
blood vessels, MR; brain, diffusion; brain, infarction; brain, MR; brain, perfusion; magnetic resonance (MR), diffusion study; magnetic resonance (MR), perfusion study; magnetic resonance (MR), vascular studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Karonen, JO Kuopio Univ Hosp, Dept Clin Radiol, Puijonlaaksontie 2, FIN-70210 Kuopio, Finland Kuopio Univ Hosp Puijonlaaksontie 2 Kuopio Finland FIN-70210
Citazione:
J.O. Karonen et al., "Combined perfusion- and diffusion-weighted MR imaging in acute ischemic stroke during the 1st week: A longitudinal study", RADIOLOGY, 217(3), 2000, pp. 886-894

Abstract

PURPOSE: To compare findings with different magnetic resonance (MR) perfusion maps in acute ischemic stroke. MATERIALS AND METHODS: Combined diffusion-weighted (DW) and perfusion-weighted (PW) MR imaging was performed in 49 patients with acute (<24 hours) stroke, on the ist and 2nd days and 1 week after stroke. Volumes of hypoperfused tissue on maps of relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), and mean transit time (MTT) were compared with the volume of infarcted tissue at DW imaging. RESULTS: The mean infarct Volume increased from 41 to 65 cm(3) between theist and 2nd days (P < .001; n = 49). On the 7st day, all perfusion maps onaverage showed hypoperfusion lesions larger than the infarct at DW imaging(P < .001; n = 49). MTT maps showed significantly (P < .001) larger hypoperfusion lesions than did rCBF maps, which showed significantly (P < .001) larger hypoperfusion lesions than did rCBV maps. The sizes of the initial perfusion-diffusion mismatches correlated significantly with the extent of infarct growth (0.479 < r < 0.657; P <less than or equal to> .001). The hypoperfusion volume on the initial rCBV maps correlated best with the final infarct size at 1 week (r = 0.891; P < .001). CONCLUSION: Combined DW and PW imaging is a powerful tool in evaluating the hemodynamics of acute ischemic stroke.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 04:21:38