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Titolo:
F-18-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies
Autore:
Hu, XS; Okamura, N; Arai, H; Higuchi, M; Matsui, T; Tashiro, M; Shinkawa, M; Itoh, M; Ido, T; Sasaki, H;
Indirizzi:
Tohoku Univ, Sch Med, Dept Geriatr Med, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 ed, Sendai, Miyagi 9808574, Japan Tohoku Univ, Ctr Cyclotron & Radioisotope, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 pe, Sendai, Miyagi 9808574, Japan
Titolo Testata:
NEUROLOGY
fascicolo: 10, volume: 55, anno: 2000,
pagine: 1575 - 1576
SICI:
0028-3878(20001128)55:10<1575:FPSOSD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Arai, H Tohoku Univ, Sch Med, Dept Geriatr Med, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 ai, Miyagi 9808574, Japan
Citazione:
X.S. Hu et al., "F-18-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies", NEUROLOGY, 55(10), 2000, pp. 1575-1576

Abstract

Using F-18-fluorodopa PET and a constant 0.0062 influx rate in the putamen, dementia with Lewy bodies (n = 7) was distinguished from AD (n = 10) witha sensitivity of 86% and a specificity of 100%. A constant 0.0071 influx rate in the caudate yielded a sensitivity of 71% and a specificity of 100% for distinction of the two disorders. Despite a limited sample size, these findings suggest that assessing nigrostriatal dopaminergic function with F-18-fluorodopa PET may be a useful diagnostic aid in cases of dementia with Lewy bodies while patients are alive.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 07:32:51