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Titolo:
X-linked loci of Drosophila melanogaster causing defects in the morphologyof the embryonic salivary glands
Autore:
Lammel, U; Saumweber, H;
Indirizzi:
Humboldt Univ, Inst Biol, Abt Zytogenet, D-10115 Berlin, Germany Humboldt Univ Berlin Germany D-10115 Zytogenet, D-10115 Berlin, Germany
Titolo Testata:
DEVELOPMENT GENES AND EVOLUTION
fascicolo: 11, volume: 210, anno: 2000,
pagine: 525 - 535
SICI:
0949-944X(200011)210:11<525:XLODMC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-SHAPE CHANGES; LARVAL CUTICLE; ZYGOTIC LOCI; TWISTED GASTRULATION; EARLY NEUROGENESIS; GENE ACTIVITY; MUTATIONS; PATTERN; CHROMOSOME; BRINKER;
Keywords:
organogenesis; embryonic lethal mutations; enhancer trap; lacZ staining;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Saumweber, H Humboldt Univ, Inst Biol, Abt Zytogenet, Chausseestr 117, D-10115 Berlin, Germany Humboldt Univ Chausseestr 117 Berlin Germany D-10115 Germany
Citazione:
U. Lammel e H. Saumweber, "X-linked loci of Drosophila melanogaster causing defects in the morphologyof the embryonic salivary glands", DEV GENES E, 210(11), 2000, pp. 525-535

Abstract

To identify X chromosomal genes required for salivary gland development inthe Drosophila embryo, we screened embryos hemizygous for EMS-induced lethal mutations to find mutations causing gross morphological defects in salivary gland development. The parental strain carried a lac Z transgene on thesecond chromosome, which was specifically expressed in the salivary glandsso the mutations could be unambiguously identified. Embryos from 3,383 lines were tested for salivary,oland abnormalities following lacZ staining. From 63 lines exhibiting aberrant salivary gland phenotypes, 52 stable lines were established containing mutations affecting salivary gland development. From these, 39 lines could be assigned to nine complementation groups: armadillo, brinker, folded gastrulation, giant, hindsight, Notch, runt, stardust and twisted gastrulation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 09:54:00