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Titolo:
Determinants of thyroid volume as measured by ultrasonography in healthy adults randomly selected
Autore:
Gomez, JM; Maravall, FJ; Gomez, N; Guma, A; Soler, J;
Indirizzi:
Ciudad Sanitaria & Univ Bellvitge, Serv Endocrinol, Barcelona, Spain Ciudad Sanitaria & Univ Bellvitge Barcelona Spain nol, Barcelona, Spain Ciudad Sanitaria & Univ Bellvitge, Serv Radiol, Barcelona, Spain Ciudad Sanitaria & Univ Bellvitge Barcelona Spain iol, Barcelona, Spain
Titolo Testata:
CLINICAL ENDOCRINOLOGY
fascicolo: 5, volume: 53, anno: 2000,
pagine: 629 - 634
SICI:
0300-0664(200011)53:5<629:DOTVAM>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MILD IODINE DEFICIENCY; CIGARETTE-SMOKING; URINARY IODINE; GLAND VOLUME; ULTRASOUND; GOITER; SCHOOLCHILDREN; THYROGLOBULIN; EXCRETION; SIZE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Gomez, JM C Sabino de Arana 40,3,2, Barcelona 08028, Spain C Sabino de Arana 40,3,2 Barcelona Spain 08028 na 08028, Spain
Citazione:
J.M. Gomez et al., "Determinants of thyroid volume as measured by ultrasonography in healthy adults randomly selected", CLIN ENDOCR, 53(5), 2000, pp. 629-634

Abstract

OBJECTIVES The relationship between thyroid volume and anthropometric characteristics is a matter of controversy. The aim of this study was to investigate thyroid volume and its determinants in healthy adult subjects from a noniodine-deficient area. DESIGN AND PATIENTS Of the 280 000 inhabitants of the city, served by L'Hospitalet de Llobregat, we randomly selected 880 subjects from the census ofthe city. The participation rate in the study was 44%; after application of several exclusion criteria, a further 28 subjects were excluded because of previously diagnosed thyroid disease. We finally studied 268 subjects representative of the census of the city: 134 male and 134 female, without thyroid disease. We determined the anthropometric characteristics, body mass index, waist-hip ratio, body surface area; body composition by bioelectricalimpedance analyser; thyroid volume by ultrasonography; basal TSH, antithyroid antibodies and urinary iodine excretion. RESULTS Thyroid volume in our population was higher in males (9.19 ml, CI 9.09-10.65) than in females (6.19 ml, CI 6.02-6.92), P = 0.001. Significantcorrelations were found among thyroid volume and body weight (r = 0.39, P = 0.0001), height (r = 0.44, P = 0.0001), body mass index (r = 0.13, P = 0.02), waist-hip ratio (r = 0.38, P = 0.0001), body surface area (r = 0.48, P= 0.0001), total body water (r = 0.14, P = 0.02), free fat mass (r = 0.47,P = 0.0001), fat mass (r = 0.37, P = 0.001) and body fat (r = 0.32, P = 0.001). Negative correlation was found between thyroid volume and basal TSH (r = -0.26, P = 0.001). No correlations were found among thyroid volume and iodine excretion, previous pregnacies in women, cigarette smoking and alcohol consumption. In a multiple regression analysis with thyroid volume as the dependent variable, body surface area was demonstrated to account for the44% of variation of thyroid volume (P = 0.0001). CONCLUSIONS It is important to know the reference values of the thyroid volume in a population free of iodine deficiency and its determinants. Body surface area accounts for much of the variation of thyroid volume. Age, gender, anthropometric variables, body composition variables and biological variables, do not significantly influence the thyroid volume when considered as possible additions to this baseline model.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 19:09:34