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Titolo:
Drug use of children in the community assessed through pharmacy dispensingdata
Autore:
Schirm, E; van den Berg, P; Gebben, H; Sauer, P; de Jong-van den Berg, L;
Indirizzi:
Univ Groningen, Ctr Pharm, Sect Social Pharm & Pharmacoepidemiol, GUIDE, NL-9713 AV Groningen, Netherlands Univ Groningen Groningen Netherlands NL-9713 AV V Groningen, Netherlands Lewenborg Pharm, Groningen, Netherlands Lewenborg Pharm Groningen Netherlands org Pharm, Groningen, Netherlands Univ Groningen Hosp, Beatrix Children Hosp, Groningen, Netherlands Univ Groningen Hosp Groningen Netherlands Hosp, Groningen, Netherlands
Titolo Testata:
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
fascicolo: 5, volume: 50, anno: 2000,
pagine: 473 - 478
SICI:
0306-5251(200011)50:5<473:DUOCIT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENERAL-PRACTICE; DANISH CHILDREN; POPULATION; PRESCRIPTIONS; SWEDEN;
Keywords:
children; drug use; drug utilization study; paediatrics; pharmacoepidemiology; pharmacy data;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Schirm, E Univ Groningen, Ctr Pharm, Sect Social Pharm & Pharmacoepidemiol, GUIDE, Antonius Deusinglaan 1, NL-9713 AV Groningen, Netherlands Univ Groningen Antonius Deusinglaan 1 Groningen Netherlands NL-9713 AV
Citazione:
E. Schirm et al., "Drug use of children in the community assessed through pharmacy dispensingdata", BR J CL PH, 50(5), 2000, pp. 473-478

Abstract

Aims To determine the extent of drug use in children and the types of drugs that children use. Methods Cross-sectional study and cohort study, using computerized pharmacy dispensing records for all children aged 0-16 years in the northern part of The Netherlands in 1998. The main outcome measures were proportion of children that used drugs (per sex and age group), mean number of drugs per child, 10 most widely used drug groups and cumulative proportions of drugs users (per drug group) during the first 2 years of life. Results Drug use was the highest among infants, decreased till adolescenceand increased from there. Overall, approximately 60% of all children used at least one drug in 1998. At younger ages, boys used more drugs than girlsand at older ages girls used more drugs than boys. Systemic antibiotics were used by 21% of the children and were by far the most widely used drugs. Other frequently used drugs were analgesics (10%), corticosteroids for dermatologic use (9%), anthistamines (8%) and antiasthmatics (7%). Approximately 10% of the children had used at least one drug at the age of 1 month and at the age of 2 years this proportion was 81%. Conclusions The majority of children was exposed to one or more drugs and this exposure started at very young age. This shows the importance of good guidelines for drug use in children and emphasizes the necessity of research of pharmacokinetic and pharmacodynamic properties in children to obtain safety, efficacy and quality evidence of these drugs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:06:08