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Titolo:
Increased anterior cingulate and caudate activity in bipolar mania
Autore:
Blumberg, HP; Stern, E; Martinez, D; Ricketts, S; de Asis, J; White, T; Epstein, J; McBride, PA; Eidelberg, D; Kocsis, JH; Silbersweig, DA;
Indirizzi:
Cornell Univ, Weill Med Coll, Dept Psychiat, Functional Neuroimaging Lab, New York, NY USA Cornell Univ New York NY USA nctional Neuroimaging Lab, New York, NY USA NYU, Sch Med, N Shore Univ Hosp, Dept Neurol, Manhasset, NY USA NYU Manhasset NY USA , N Shore Univ Hosp, Dept Neurol, Manhasset, NY USA
Titolo Testata:
BIOLOGICAL PSYCHIATRY
fascicolo: 11, volume: 48, anno: 2000,
pagine: 1045 - 1052
SICI:
0006-3223(200012)48:11<1045:IACACA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; CEREBRAL BLOOD-FLOW; MOOD DISORDERS; BASAL GANGLIA; SCHIZOPHRENIC-PATIENTS; COMPUTED-TOMOGRAPHY; SYMPTOM PROVOCATION; GLUCOSE-METABOLISM; WHITE-MATTER; CORTEX;
Keywords:
bipolar disorder; mania; affective disorders; tomography emission-computed; gyrus cinguli; caudate nucleus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Blumberg, HP Vet Adm Connecticut Healthcare Syst, Dept Psychiat 116A, 950 Campbell Ave,W Haven, CT 06516 USA Vet Adm Connecticut Healthcare Syst 950 Campbell Ave W Haven CT USA 06516
Citazione:
H.P. Blumberg et al., "Increased anterior cingulate and caudate activity in bipolar mania", BIOL PSYCHI, 48(11), 2000, pp. 1045-1052

Abstract

Background: Executive control of cognition, emotion, and behavior are disrupted in the manic state of bipolar disorder. Whereas frontal systems are implicated in such dysfunction, the localization of functional brain abnormalities in the manic state is not well understood. Methods: We utilized a high-sensitivity (H2O)-O-15 positron emission tomography technique to investigate regions of increased brain activity in mania, compared to euthymia, in bipolar disorder,Results: The principal findings were manic state-related increased activity in left dorsal anterior cingulate, and left head of caudate,Conclusions: The findings suggest that the manic state of bipolar disordermay be associated with heightened activity in a frontal cortical-subcortical neural system that includes the anterior cingulate and caudate, (C) 2000Society of Biological Psychiatry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 14:00:00