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Titolo:
Vesicoureteral reflux after kidney transplantation in children
Autore:
Ranchin, B; Chapuis, F; Dawhara, M; Canterino, I; Hadj-Aissa, A; Said, MH; Parchoux, B; Dubourg, L; Pouillaude, JM; Floret, D; Martin, X; Cochat, P;
Indirizzi:
Hop Edouard Herriot, Dept Pediat, F-69437 Lyon 03, France Hop Edouard Herriot Lyon France 03 Dept Pediat, F-69437 Lyon 03, France Hotel Dieu, Ctr Informat Med, Paris, France Hotel Dieu Paris FranceHotel Dieu, Ctr Informat Med, Paris, France Univ Lyon 1, Hop Edouard Herriot, Serv Urol & Chirurg Transplantat, F-69365 Lyon, France Univ Lyon 1 Lyon France F-69365 irurg Transplantat, F-69365 Lyon, France Univ Lyon 1, Hop Edouard Herriot, Serv Radiol Pediat, F-69365 Lyon, FranceUniv Lyon 1 Lyon France F-69365 Serv Radiol Pediat, F-69365 Lyon, France Univ Lyon 1, Hop Edouard Herriot, Serv Explorat Fonct Renale, F-69365 Lyon, France Univ Lyon 1 Lyon France F-69365 lorat Fonct Renale, F-69365 Lyon, France Univ Lyon 1, Hop Edouard Herriot, Serv Reanimat Pediat, F-69365 Lyon, France Univ Lyon 1 Lyon France F-69365 rv Reanimat Pediat, F-69365 Lyon, France
Titolo Testata:
NEPHROLOGY DIALYSIS TRANSPLANTATION
fascicolo: 11, volume: 15, anno: 2000,
pagine: 1852 - 1858
SICI:
0931-0509(200011)15:11<1852:VRAKTI>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY-TRACT INFECTIONS; RENAL-TRANSPLANTATION; CLINICAL-SIGNIFICANCE; PYELONEPHRITIS; RECIPIENTS;
Keywords:
child; kidney transplantation; renal function; urinary-tract infection; vesicoureteral reflux;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Cochat, P Hop Edouard Herriot, Dept Pediat, F-69437 Lyon 03, France Hop Edouard Herriot Lyon France 03 at, F-69437 Lyon 03, France
Citazione:
B. Ranchin et al., "Vesicoureteral reflux after kidney transplantation in children", NEPH DIAL T, 15(11), 2000, pp. 1852-1858

Abstract

Background. The prevalence and significance of vesicoureteral reflux (WR) after kidney transplantation in adults varies between authors and there have been few reports in children. Methods. We conducted a retrospective study in a single-centre paediatric cohort. Fifty-five of the 84 children who underwent kidney transplantation over a 5-year period were checked with routine cystography after a median of 8 months post-transplantation. Graft function and urinary-tract infections were assessed during the first 6 years after transplantation. Results, VUR into the graft was present in 58% of the patients. Graft function and incidence of urinary-tract infections were similar in the two groups, independent of VUR. After having excluded infections attributed to the presence of a catheter, actuarial survival rates without pyelonephritis andwithout pyelonephritis following a first lower urinary-tract infection were worse in patients with WR (P = 0.017 and P = 0.0039 respectively). None of the eight patients with WR treated with antibiotic prophylaxis after a first acute pyelonephritis (APN) episode presented subsequent APN after 4.4+/-3.3 years on therapy. Conclusions. VUR to the graft occurred in more than half paediatric renal transplant recipients. This condition was associated with an increased riskof APN. Long-term antibiotic prophylaxis seems to be able to prevent APN in transplanted children with WR.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:55:09