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Titolo:
Fatigue and basal ganglia
Autore:
Chaudhuri, A; Behan, PO;
Indirizzi:
Univ Glasgow, So Gen Hosp, Dept Neurol, Inst Neurol Sci, Glasgow G51 4TF, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland G51 4TF ow G51 4TF, Lanark, Scotland
Titolo Testata:
JOURNAL OF THE NEUROLOGICAL SCIENCES
fascicolo: 1-2, volume: 179, anno: 2000,
pagine: 34 - 42
SICI:
0022-510X(20001001)179:1-2<34:FABG>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLOGICAL DISORDERS; MULTIPLE-SCLEROSIS; PARKINSONS-DISEASE; CIRCUITS; MOTOR; ORGANIZATION; ANTEROGRADE; DYSFUNCTION; DEPRESSION; RECEPTORS;
Keywords:
fatigue; basal ganglia; limbic system; dopamine; serotanin; thalamo-cortical loop; chronic fatigue syndrome;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: Chaudhuri, A Univ Glasgow, So Gen Hosp, Dept Neurol, Inst Neurol Sci, 1345Govan Rd, Glasgow G51 4TF, Lanark, Scotland Univ Glasgow 1345 Govan Rd Glasgow Lanark Scotland G51 4TF nd
Citazione:
A. Chaudhuri e P.O. Behan, "Fatigue and basal ganglia", J NEUR SCI, 179(1-2), 2000, pp. 34-42

Abstract

Fatigue is a common symptom in neurology and occurs in the diseases of thecentral and peripheral nervous system. In order to understand the mechanism of fatigue, it is important to distinguish symptoms of peripheral neuromuscular fatigue from the symptoms of physical and mental fatigue characteristic of disorders like Parkinson's disease or multiple sclerosis. We have introduced and defined the concept of central fatigue for the latter disorders. We have further proposed, with supportive neuropathological data, that central fatigue may occur due to a failure in the integration of the limbic input and the motor functions within the basal ganglia affecting the striatal-thalamic-frontal cortical system. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 01:51:26