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Titolo:
Use of an anesthesia information management system (AIMS) to evaluate the physiologic effects of hypnotic agents used to induce anesthesia
Autore:
Benson, M; Junger, A; Fuchs, C; Quinzio, L; Bottger, S; Hempelmann, G;
Indirizzi:
Univ Giessen, Dept Anaesthesiol & Intens Care Med, D-35392 Giessen, Germany Univ Giessen Giessen Germany D-35392 Care Med, D-35392 Giessen, Germany
Titolo Testata:
JOURNAL OF CLINICAL MONITORING AND COMPUTING
fascicolo: 3, volume: 16, anno: 2000,
pagine: 183 - 190
SICI:
1387-1307(2000)16:3<183:UOAAIM>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAVENOUS INDUCTION; PROPOFOL; RECORDS; ETOMIDATE; QUALITY; EMULSION;
Keywords:
Anesthesia Information Management System (AIMS); Patient Data Management System (PDMS); quality assurance; induction hypnotics; data mining;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Benson, M Univ Giessen, Dept Anaesthesiol & Intens Care Med, Rudolf Buchheim Str 7, D-35392 Giessen, Germany Univ Giessen Rudolf Buchheim Str 7 Giessen Germany D-35392 many
Citazione:
M. Benson et al., "Use of an anesthesia information management system (AIMS) to evaluate the physiologic effects of hypnotic agents used to induce anesthesia", J CLIN M C, 16(3), 2000, pp. 183-190

Abstract

Objective. The aim of this study was to utilize an anesthesia information management system (AIMS) in investigating the effects of hypnotic agents used to induce anesthesia on blood pressure, heart rate and arterial oxygen saturation. The characteristics of these agents, known from previous studies, were compared to the effects documented in this study during routine clinical use. Methods. During the years 1997 and 1998, all relevant data from anesthetic procedures were recorded online using the automated anesthesia information system NarkoData. The data from 8,078 general anesthesia procedures using endotracheal intubation were exported via "structured query language" (SQL) from the AIMS database into a statistics program after excluding children (age < 14), patients who received atropine during induction and procedures with use of extracorporeal circulation. The effects of drug administration on systolic, diastolic and mean arterial blood pressure (SBP, DBP,MBP), heart rate (HR) and arterial oxygen saturation (SpO(2)) were analyzed prior to induction and at 5, 10 and 15 minutes following bolus administration of the hypnotic agent. The data were classified into three groups based on the induction agent used: thiopental, etomidate or propofol and further separated into two groups based on ASA status (ASA less than or equal to II and ASA > II). The mean and standard deviations were calculated for eachparameter at each point in time. Statistical comparisons were performed todetermine whether the results for each time point differed from the previous time point. Results. There was a significant decrease in blood pressure (MAP, SBP, DBP) after bolus administration of all three hypnotics in all ofthe 8,078 procedures analyzed. The decrease was greater in patients of ASAclass > II than in those of ASA class less than or equal to II. Propofol caused the greatest drop in blood pressure whereas etomidate caused the least. During the observation period the HR also fell in each group, except forthiopental where an initial rise of the HR could be observed. An initial rise of SpO(2) was recorded in each group with no differences observed between the individual hypnotics. Conclusions. The effects of the induction hypnotic agents thiopental, etomidate and propofol on blood pressure and heart rate as documented by an AIMS corresponded to those found in clinical studies. An AIMS with the corresponding documentation, software and database structure is suitable for collecting and evaluating data for clinical investigations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:27:22