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Titolo:
Lung function measured by the oscillometric method in prematurely born children with chronic lung disease
Autore:
Malmberg, LP; Mieskonen, S; Pelkonen, A; Kari, A; Sovijarvi, ARA; Turpeinen, M;
Indirizzi:
Univ Helsinki, Cent Hosp, Dept Allerg Dis, FIN-00029 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00029 is, FIN-00029 Helsinki, Finland Univ Helsinki, Cent Hosp, Hosp Children & Adolescents, FIN-00029 Helsinki,Finland Univ Helsinki Helsinki Finland FIN-00029 nts, FIN-00029 Helsinki,Finland Univ Helsinki, Cent Hosp, Dept Lab, FIN-00029 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00029 ab, FIN-00029 Helsinki, Finland
Titolo Testata:
EUROPEAN RESPIRATORY JOURNAL
fascicolo: 4, volume: 16, anno: 2000,
pagine: 598 - 603
SICI:
0903-1936(200010)16:4<598:LFMBTO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
FORCED OSCILLATION TECHNIQUE; BRONCHOPULMONARY DYSPLASIA; ASTHMATIC-CHILDREN; PULMONARY-FUNCTION; RESPIRATORY RESISTANCE; BODY PLETHYSMOGRAPHY; CYSTIC-FIBROSIS; SCHOOL-AGE; RESPONSIVENESS; METHACHOLINE;
Keywords:
bronchopulmonary dysplasia; chronic lung disease; forced oscillation; prematurity; respiratory function tests;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Malmberg, LP Univ Helsinki, Cent Hosp, Dept Allerg Dis, POB 160, FIN-00029Helsinki, Finland Univ Helsinki POB 160 Helsinki Finland FIN-00029 ki, Finland
Citazione:
L.P. Malmberg et al., "Lung function measured by the oscillometric method in prematurely born children with chronic lung disease", EUR RESP J, 16(4), 2000, pp. 598-603

Abstract

Premature birth is related to a chronic respiratory morbidity, which may persist until school-age. In these children, the forced oscillation technique would be suitable for evaluation of lung function even at preschool age, since it requires only minimal patient cooperation. In order to investigate the oscillometric findings related to premature birth, using the oscillation technique and conventional lung function methods49 school-aged children born prematurely with (n=15) or without (n=34) chronic lung disease (CLD), and 18 healthy children born at full term mere studied. Children with CLD had higher respiratory resistance (Rrs,5) and lower reactance (Xrs,5) than prematurely born children without CLD or healthy controls. Both Rrs,5 (r=-0.55, p<0.0001) and Xrs,5 (r=0.76, p<0.0001) were significantly associated with forced expiratory volume in one second (FEV1), the agreement with spirometry being better in Xrs,5 than in Xrs,5 (p=0.02). Rrs,5 was significantly related to airway resistance (Raw) measured by body plethysmography (r=0.63, p<0.0001), but underestimated resistance at high values of Raw. There was no significant relationship between the pulmonary diffusing capacity and the oscillometric findings. Compared to conventional methods, the oscillometric method yields concordant information on the severity of lung function deficit in children born prematurely, with or without chronic lung disease, In these children, the oscillometric findings are probably due to peripheral or more widespread airway obstruction. As conventional methods are not usually suitable for preschool children, oscillometry may serve as an alternative for early evaluation of chronic lung disease among children with premature birth in clinical or research settings.

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Documento generato il 02/04/20 alle ore 02:05:25