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Titolo:
Quantitatively assessed coronary collateral circulation and restenosis following percutaneous revascularization
Autore:
Wahl, A; Billinger, M; Fleisch, M; Meier, B; Seiler, C;
Indirizzi:
Univ Hosp Bern, Swiss Cardiovasc Ctr Bern, CH-3010 Bern, Switzerland Univ Hosp Bern Bern Switzerland CH-3010 Bern, CH-3010 Bern, Switzerland
Titolo Testata:
EUROPEAN HEART JOURNAL
fascicolo: 21, volume: 21, anno: 2000,
pagine: 1776 - 1784
SICI:
0195-668X(200011)21:21<1776:QACCCA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
BALLOON ANGIOPLASTY; PRESSURE MEASUREMENTS; ARTERY DISEASE; ASYMPTOMATIC RESTENOSIS; WEDGE PRESSURE; FLOW; VARIABLES;
Keywords:
coronary artery disease; coronary collateral circulation; intracoronary pressure measurements; angiography; percutaneous transluminal coronary angioplasty; restenosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Seiler, C Univ Hosp Bern, Swiss Cardiovasc Ctr Bern, CH-3010 Bern, Switzerland Univ Hosp Bern Bern Switzerland CH-3010 3010 Bern, Switzerland
Citazione:
A. Wahl et al., "Quantitatively assessed coronary collateral circulation and restenosis following percutaneous revascularization", EUR HEART J, 21(21), 2000, pp. 1776-1784

Abstract

Aims A high degree of collateral supply to a vascular area where a percutaneous transluminal coronary angioplasty (PTCA) has been performed represents a haemodynamic force competing with the antegrade flow through the dilated lesion. Therefore, our purpose was to determine whether patients with restenosis following PTCA have a higher collateral flow to the recipient vessel than patients without restenosis. Methods and Results In 200 consecutive PTCA patients, an intracoronary pressure-derived collateral Row index (CFI) was determined quantitatively during balloon occlusion, using simultaneous measurements of the mean aortic pressure (P-ao) and of the intracoronary pressure distal to the occluded stenosis (P-occl), as well as the estimated central venous pressure (CVP=5 mmHg): CFI=(P-occl-CVP)/(P-ao-CVP). Sixty-four patients had an angiographic follow-up examination after at least 2 months, and were subdivided into patients with restenosis (>50% diameter stenosis, n=34) and patients without restenosis (n=30). Patients with restenosis had a significantly higher collateral how index at the initial coronary angiography than patients without restenosis (0.26 +/- 0.14 vs 0.12 +/- 0.09: P<0.0001). Conclusions Patients with restenosis after PTCA show a more extended collateral supply to this recipient area than patients without restenosis. Well developed collaterals to a revascularized region are a risk factor for restenosis of the treated lesion. (Eur Heart J 2000; 21: 1776-1784, doi:10.1053/euhj.2000. 2129) (C) 2000 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:10:00