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Titolo:
Influence of the consumption of fatty Baltic Sea fish on plasma levels of halogenated environmental contaminants in Latvian and Swedish men
Autore:
Sjodin, A; Hagmar, L; Klasson-Wehler, E; Bjork, J; Bergman, A;
Indirizzi:
Stockholm Univ, Dept Environm Chem, Wallenberg Lab, SE-10691 Stockholm, Sweden Stockholm Univ Stockholm Sweden SE-10691 Lab, SE-10691 Stockholm, Sweden Univ Lund Hosp, Dept Occupat & Environm Med, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 & Environm Med, S-22185 Lund, Sweden
Titolo Testata:
ENVIRONMENTAL HEALTH PERSPECTIVES
fascicolo: 11, volume: 108, anno: 2000,
pagine: 1035 - 1041
SICI:
0091-6765(200011)108:11<1035:IOTCOF>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYBROMINATED DIPHENYL ETHERS; PERCH PERCA-FLUVIATILIS; POLYCHLORINATED-BIPHENYLS; HUMAN-MILK; ORGANOCHLORINE COMPOUNDS; THYROXINE-BINDING; FLAME-RETARDANT; BLOOD-PLASMA; TRANSTHYRETIN; METABOLITES;
Keywords:
endocrine disruptors; fish consumption; hexachlorobenzene; pentachlorophenol; polychlorobiphenylols; polybrominated diphenyl ethers; thyroid hormone;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: Bergman, A Stockholm Univ, Dept Environm Chem, Wallenberg Lab, SE-10691 Stockholm, Sweden Stockholm Univ Stockholm Sweden SE-10691 91 Stockholm, Sweden
Citazione:
A. Sjodin et al., "Influence of the consumption of fatty Baltic Sea fish on plasma levels of halogenated environmental contaminants in Latvian and Swedish men", ENVIR H PER, 108(11), 2000, pp. 1035-1041

Abstract

We examined the influence of widely varied consumption of fatty fish from the Baltic Sea and of age on plasma concentrations of polychlorinated biphenyls (PCBs), polychlorobiphenylols (OH-PCBs), 2,2-bis(4-chlorophenyl)-1,1,1-trichloroethane (4,4'-DDT), 2,2-bis(4-chlorophenyl)-1,1-dichloroechane (4,4'-DDE), 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), hexachlorobenzene (HCB), and pentachlorophenol (PCP) in Latvian and Swedish men. Both age and fish consumption were significantly correlated with the concentrations of Sigma PCB, Sigma OH-PCB, 4,4'-DDE, 4,4'-DDT, and HCB. In the case of BDE-47, no significant relationship with age was observed, and fish consumption had the largest relative effect on plasma concentrations of this contaminant. This relationship may be a result of exposure to BDE-47 having been more recent than that of PCBs and DDE, or because the half-life of BDE-47 may be shorter than that of PCB and DDE. Latvian men demonstrated higher plasma levels of DDE and DDT bur lower levels of Sigma PCB and PCP than did Swedish men. The corresponding levels of HCB and BDE-47 were similar in both countries. The Spearman's rank correlation coefficient obtained by comparing the level of the metabolite 4-hydroxy-2,3,3',4',5-pentachlorobipheny (4-OH-CB107)to the combined levels of its parent compounds, 2,3,3',4,4'-pentachlorobiphenyl (CB-105) and 2,3',4,4',5-pentachlorobiphenyl (CB-118), was higher than the median correlation coefficient obtained upon comparing the level of this metabolite to all other possible combinations of two PCB levels. No other increased correlation between metabolite and parent PCB concentration was observed.

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Documento generato il 06/04/20 alle ore 02:13:47