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Titolo:
LUNG-VOLUMES DURING SUSTAINED MICROGRAVITY ON SPACELAB SLS-1
Autore:
ELLIOTT AR; PRISK GK; GUY HJB; WEST JB;
Indirizzi:
UNIV CALIF SAN DIEGO,DEPT MED,0931,9500 GILMAN DR LA JOLLA CA 92093
Titolo Testata:
Journal of applied physiology
fascicolo: 4, volume: 77, anno: 1994,
pagine: 2005 - 2014
SICI:
8750-7587(1994)77:4<2005:LDSMOS>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
SHORT PERIODS; BLOOD-VOLUME; CHEST; MECHANICS; IMMERSION; NECK;
Keywords:
HUMANS; SPACEFLIGHT; ZERO GRAVITY; TIDAL VOLUME; EXPIRATORY RESERVE VOLUME; RESIDUAL VOLUME; INSPIRATORY VITAL CAPACITY; EXPIRATORY VITAL CAPACITY; FUNCTIONAL RESIDUAL CAPACITY; TOTAL LUNG CAPACITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
A.R. Elliott et al., "LUNG-VOLUMES DURING SUSTAINED MICROGRAVITY ON SPACELAB SLS-1", Journal of applied physiology, 77(4), 1994, pp. 2005-2014

Abstract

Gravity is known to influence the mechanical behavior of the lung andchest wall. However, the effect of sustained microgravity (mu G) on lung volumes has not been reported. Pulmonary function tests were performed by four subjects before, during, and after 9 days of mu G exposure. Ground measurements were made in standing and supine postures. Tests were performed using a bag-in-box-and-flowmeter system and a respiratory mass spectrometer. Measurements included functional residual capacity (FRC), expiratory reserve volume (ERV), residual volume (RV), inspiratory and expiratory vital capacities (IVC and EVC), and tidal volume (VT). Total lung capacity (TLC) was derived from the measured EVC and RV values. With preflight standing values as a comparison, FRC was significantly reduced by 15% (similar to 500 ml) in mu G and 32% in the supine posture. ERV was reduced by 10-20% in mu G and decreased by 64% in the supine posture. RV was significantly reduced by 18% (310 ml)in mu G but did not significantly change in the supine posture compared with standing. IVC and EVC were slightly reduced during the first 24 h of mu G but returned to 1-G standing values within 72 h of mu G exposure. IVC and EVC in the supine posture were significantly reduced by 12% compared with standing. During mu G, VT decreased by 15% (similar to 90 ml), but supine VT was unchanged compared with preflight standing values. TLC decreased by similar to 8% during mu G and in the supine posture compared with preflight standing. The reductions in FRC, ERV, and RV during mu G are probably due to the cranial shift of the diaphragm, an increase in intrathoracic blood volume, and more uniform alveolar expansion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 17:23:44