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Titolo:
The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective
Autore:
Semino, O; Passarino, G; Oefner, PJ; Lin, AA; Arbuzova, S; Beckman, LE; De Benedictis, G; Francalacci, P; Kouvatsi, A; Limborska, S; Marcikiae, M; Mika, A; Mika, B; Primorac, D; Santachiara-Benerecetti, AS; Cavalli-Sforza, LL; Underhill, PA;
Indirizzi:
Univ Pavia, Dipartimento Genet & Microbiol, I-27100 Pavia, Italy Univ Pavia Pavia Italy I-27100 o Genet & Microbiol, I-27100 Pavia, Italy Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 d, Dept Genet, Stanford, CA 94305 USA Univ Calabria, Dipartimento Biol Cellulare, I-87030 Rende, Italy Univ Calabria Rende Italy I-87030 o Biol Cellulare, I-87030 Rende, Italy Stanford Genome Technol Ctr, Palo Alto, CA 94304 USA Stanford Genome Technol Ctr Palo Alto CA USA 94304 alo Alto, CA 94304 USA Hosp Nol, Int Medicogenet Ctr, UA-340000 Donetsk, Ukraine Hosp Nol Donetsk Ukraine UA-340000 genet Ctr, UA-340000 Donetsk, Ukraine Umea Univ, Dept Oncoll Pathol & Med Genet, S-90185 Umea, Sweden Umea UnivUmea Sweden S-90185 l Pathol & Med Genet, S-90185 Umea, Sweden Univ Sassari, Dipartimento Zool & Antropol Biol, I-07100 Sassari, Italy Univ Sassari Sassari Italy I-07100 Antropol Biol, I-07100 Sassari, Italy Aristotelian Univ Salonika, Dept Genet Dev & Mol Biol, GR-54006 Salonika, Macedonia, Greece Aristotelian Univ Salonika Salonika Macedonia Greece GR-54006 nia, Greece Russian Acad Sci, Inst Mol Genet, Moscow 123182, Russia Russian Acad Sci Moscow Russia 123182 t Mol Genet, Moscow 123182, Russia Clin Hosp Ctr Osijek, Sch Med, Dept Pathol, Osijek 31000, Croatia Clin Hosp Ctr Osijek Osijek Croatia 31000 Pathol, Osijek 31000, Croatia Reg Ctr Krwiodawstwa & Krwioleczny Lublinie Oddzi, PL-22400 Zamosc, PolandReg Ctr Krwiodawstwa & Krwioleczny Lublinie Oddzi Zamosc Poland PL-22400 Univ Hosp Split, Dept Pediat, Lab Clin & Forens Genet, Split 21000, Croatia Univ Hosp Split Split Croatia 21000 & Forens Genet, Split 21000, Croatia Samodzielny Publ Szpital Wojwodzki Papieza Jona P, PL-22400 Zamosc, PolandSamodzielny Publ Szpital Wojwodzki Papieza Jona P Zamosc Poland PL-22400
Titolo Testata:
SCIENCE
fascicolo: 5494, volume: 290, anno: 2000,
pagine: 1155 - 1159
SICI:
0036-8075(20001110)290:5494<1155:TGLOPH>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICROSATELLITE LOCI; NATIVE-AMERICAN; POLYMORPHISMS; DNA; POPULATIONS; MARKERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Semino, O Univ Pavia, Dipartimento Genet & Microbiol, Via Ferrata 1, I-27100 Pavia, Italy Univ Pavia Via Ferrata 1 Pavia Italy I-27100 27100 Pavia, Italy
Citazione:
O. Semino et al., "The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective", SCIENCE, 290(5494), 2000, pp. 1155-1159

Abstract

A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European genepool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.

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Documento generato il 27/11/20 alle ore 07:27:11