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Titolo:
Y chromosome sequence variation and the history of human populations
Autore:
Underhill, PA; Shen, PD; Lin, AA; Jin, L; Passarino, G; Yang, WH; Kauffman, E; Bonne-Tamir, B; Bertranpetit, J; Francalacci, P; Ibrahim, M; Jenkins, T; Kidd, JR; Mehdi, SQ; Seielstad, MT; Wells, RS; Piazza, A; Davis, RW; Feldman, MW; Cavalli-Sforza, LL; Oefner, PJ;
Indirizzi:
Stanford Univ, Dept Genet, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 v, Dept Genet, Stanford, CA 94305 USA Stanford DNA Sequencing & Technol Ctr, Palo Alto, CA USA Stanford DNA Sequencing & Technol Ctr Palo Alto CA USA Palo Alto, CA USA Univ Texas, Ctr Human Genet, Houston, TX USA Univ Texas Houston TX USAUniv Texas, Ctr Human Genet, Houston, TX USA Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 ac Med, IL-69978 Tel Aviv, Israel Univ Pompeu Fabra, Fac Ciencies Salut Vida, Unitat Biol Evolut, Barcelona,Spain Univ Pompeu Fabra Barcelona Spain , Unitat Biol Evolut, Barcelona,Spain Univ Sassari, Dipartimento Zool & Antropol Biol, I-07100 Sassari, Italy Univ Sassari Sassari Italy I-07100 Antropol Biol, I-07100 Sassari, Italy Univ Khartoum, Inst Endem Dis, Khartoum, Sudan Univ Khartoum Khartoum Sudan Khartoum, Inst Endem Dis, Khartoum, Sudan S African Inst Med Res, Sch Pathol, Dept Human Genet, Johannesburg, South Africa S African Inst Med Res Johannesburg South Africa nnesburg, South Africa Univ Witwatersrand, Johannesburg, South Africa Univ Witwatersrand Johannesburg South Africa Johannesburg, South Africa Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA Yale Univ New Haven CT USA 06510 Med, Dept Genet, New Haven, CT 06510 USA Biomed & Genet Engn Labs, Dr AQ Khan Res Labs, Islamabad, Pakistan Biomed & Genet Engn Labs Islamabad Pakistan s Labs, Islamabad, Pakistan Harvard Univ, Sch Publ Hlth, Program Populat Genet, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 gram Populat Genet, Boston, MA 02115 USA Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX1 2JD, England Univ Oxford Oxford England OX1 2JD Human Genet, Oxford OX1 2JD, England Univ Turin, Dept Genet, Dept Genet Biol & Biochem, Turin, Italy Univ Turin Turin Italy t Genet, Dept Genet Biol & Biochem, Turin, Italy Stanford Univ, Dept Biol Sci, Herrin Labs, Stanford, CA 94305 USA StanfordUniv Stanford CA USA 94305 , Herrin Labs, Stanford, CA 94305 USA
Titolo Testata:
NATURE GENETICS
fascicolo: 3, volume: 26, anno: 2000,
pagine: 358 - 361
SICI:
1061-4036(200011)26:3<358:YCSVAT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC-EVIDENCE; HAPLOTYPES; AFRICA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Underhill, PA Stanford Univ, Dept Genet, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 Stanford, CA 94305 USA
Citazione:
P.A. Underhill et al., "Y chromosome sequence variation and the history of human populations", NAT GENET, 26(3), 2000, pp. 358-361

Abstract

Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic: legacy of our species that has persisted to the present, permitting inference of human evolution,population affinity and demographic history(1). We used denaturing highperformance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious; genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 19:52:55